The evolution of gene expression in cis and trans

SA Signor, SV Nuzhdin - Trends in Genetics, 2018 - cell.com
There is abundant variation in gene expression between individuals, populations, and
species. The evolution of gene regulation and expression within and between species is …

Gene regulation and speciation

KL Mack, MW Nachman - Trends in Genetics, 2017 - cell.com
Understanding the genetic architecture of speciation is a major goal in evolutionary biology.
Hybrid dysfunction is thought to arise most commonly through negative interactions between …

[HTML][HTML] Transcriptional programs of circuit assembly in the Drosophila visual system

YZ Kurmangaliyev, J Yoo, J Valdes-Aleman… - Neuron, 2020 - cell.com
Precise patterns of synaptic connections between neurons are encoded in their genetic
programs. Here, we use single-cell RNA sequencing to profile neuronal transcriptomes at …

Experimental evolution of gene expression and plasticity in alternative selective regimes

Y Huang, AF Agrawal - PLoS genetics, 2016 - journals.plos.org
Little is known of how gene expression and its plasticity evolves as populations adapt to
different environmental regimes. Expression is expected to evolve adaptively in all …

Environmentally robust cis-regulatory changes underlie rapid climatic adaptation

MA Ballinger, KL Mack, SM Durkin… - Proceedings of the …, 2023 - National Acad Sciences
Changes in gene expression are thought to play a major role in adaptive evolution. While it
is known that gene expression is highly sensitive to the environment, very few studies have …

Viruses in Laboratory Drosophila and Their Impact on Host Gene Expression

O Kuyateh, DJ Obbard - Viruses, 2023 - mdpi.com
Drosophila melanogaster has one of the best characterized antiviral immune responses
among invertebrates. However, relatively few easily transmitted natural virus isolates are …

Drosophila melanogaster as a Translational Model System to Explore the Impact of Phytochemicals on Human Health

C Lopez-Ortiz, C Gracia-Rodriguez, S Belcher… - International Journal of …, 2023 - mdpi.com
Fruits, vegetables, and spices are natural sources of bioactive phytochemicals, such as
polyphenols, carotenoids, flavonoids, curcuminoids, terpenoids, and capsaicinoids …

Allele-specific regulatory effects on the pig transcriptome

Y Lin, J Li, L Chen, J Bai, J Zhang, Y Wang, P Liu… - …, 2023 - academic.oup.com
Background Allele-specific expression (ASE) refers to the preferential expression of one
allele over the other and contributes to adaptive phenotypic plasticity. Here, we used a …

Variation in Pleiotropic Hub Gene Expression Is Associated with Interspecific Differences in Head Shape and Eye Size in Drosophila

E Buchberger, A Bilen, S Ayaz… - Molecular biology …, 2021 - academic.oup.com
Revealing the mechanisms underlying the breathtaking morphological diversity observed in
nature is a major challenge in Biology. It has been established that recurrent mutations in …

Improving estimates of compensatory cis–trans regulatory divergence

HB Fraser - Trends in Genetics, 2019 - cell.com
Interspecific hybrids have played a key role in research on gene expression regulation. A
growing number of studies have measured genome-wide allele-specific expression in …