In the search for new sources of antimicrobials many researchers have investigated
antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics …

Leishmaniasis, a category 1 neglected protozoan disease caused by a kinetoplastid
pathogen called Leishmania, is transmitted through dipteran insect vectors (phlebotomine …

Antimicrobial peptides (AMPs) have appeared as promising compounds to treat a wide
range of diseases. Their clinical potentialities reside in the wide range of mechanisms they …

Antimicrobial peptides (AMPs) are promising drugs to kill resistant pathogens. In contrast to
bacteria, protozoan parasites, such as Leishmania, were little studied. Therefore, the …

Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …

Phospholipase A 2 toxins present in snake venoms interact with biological membranes and
serve as structural models for the design of small peptides with anticancer, antibacterial and …

Cationic peptides bio-inspired by natural toxins have been recognized as an efficient
strategy for the treatment of different health problems. Due to the specific interaction with …

Leishmaniasis is one of the major neglected tropical diseases of the world. It is present in 88
countries with an estimated number of 500,000 cases of visceral leishmaniasis and 1.5 …

The toxicity of available drugs for treatment of leishmaniasis, coupled with emerging drug
resistance, make it urgent to find new therapies. Antimicrobial peptides (AMPs) have a …

Visceral leishmaniasis (VL) is among the most neglected tropical diseases in the world.
Drug cell permeability is essential for killing the intracellular residing parasites responsible …