Although hypothyroidism appears to be an important factor in the pathogenesis of
depression, the impact of thyroid hormones on the bioenergetics of the adult brain is still …

Background: Post-stroke depression (PSD) is a mental health condition that can develop
after a stroke, with a higher risk of death and negative outcomes. However, limited research …

Metabolic disturbances in the brain are assumed to be early changes involved in the
pathogenesis of depression, and these alterations may be intensified by a deficiency of …

Current data suggest an important role of brain metabolic disturbances in the pathogenesis
of depression and obesity, diseases that frequently co-occur. Our aim was to determine …

Depression and anxiety often co-occur with cardiac diseases. The Shexiang Baoxin pill
(SBP) is a proprietary Chinese medicine initially used to treat cardiac conditions. This study …

Alteration in reproductive hormones profile is associated with the increasing risk of
menopausal depression in women. Serum follicle-stimulating hormone (FSH) level is …

The HSP70 and HSP90 family members belong to molecular chaperones that exhibit
protective functions during the cellular response to stressful agents. We investigated …

Background In depression, excessive glucocorticoid action may cause maladaptive brain
changes, including in the pathways controlling energy metabolism. Insulin and glucagon …

There is a high level of comorbidity between depression and alcohol use disorder.
Subanesthetic doses of ketamine induce short-acting and enduring antidepressant effects …

Objective: This study aimed to examine the effects of prenatal stress (PS) induced by
dexamethasone exposure on gene expression levels of epigenetic enzymes in …