[HTML][HTML] Impaired brain energy metabolism: involvement in depression and hypothyroidism
K Głombik, J Detka, A Kurek… - Frontiers in …, 2020 - frontiersin.org
Although hypothyroidism appears to be an important factor in the pathogenesis of
depression, the impact of thyroid hormones on the bioenergetics of the adult brain is still …
depression, the impact of thyroid hormones on the bioenergetics of the adult brain is still …
[HTML][HTML] Association of lesion location with post-stroke depression in China: a systematic review and meta-analysis
X Luo, W Fang, J Ji, Y Zhang… - EC psychology and …, 2023 - ncbi.nlm.nih.gov
Background: Post-stroke depression (PSD) is a mental health condition that can develop
after a stroke, with a higher risk of death and negative outcomes. However, limited research …
after a stroke, with a higher risk of death and negative outcomes. However, limited research …
[HTML][HTML] Changes in regulators of lipid metabolism in the brain: a study of animal models of depression and hypothyroidism
K Głombik, J Detka, M Kukla-Bartoszek… - Pharmacological …, 2022 - Springer
Metabolic disturbances in the brain are assumed to be early changes involved in the
pathogenesis of depression, and these alterations may be intensified by a deficiency of …
pathogenesis of depression, and these alterations may be intensified by a deficiency of …
[HTML][HTML] Brain metabolic alterations in rats showing depression-like and obesity phenotypes
K Głombik, J Detka, J Góralska, A Kurek, B Solnica… - Neurotoxicity …, 2020 - Springer
Current data suggest an important role of brain metabolic disturbances in the pathogenesis
of depression and obesity, diseases that frequently co-occur. Our aim was to determine …
of depression and obesity, diseases that frequently co-occur. Our aim was to determine …
[HTML][HTML] Antidepressant and anxiolytic effects of the proprietary Chinese medicine Shexiang Baoxin pill in mice with chronic unpredictable mild stress
XD Zhou, DD Shi, ZJ Zhang - journal of food and drug analysis, 2019 - Elsevier
Depression and anxiety often co-occur with cardiac diseases. The Shexiang Baoxin pill
(SBP) is a proprietary Chinese medicine initially used to treat cardiac conditions. This study …
(SBP) is a proprietary Chinese medicine initially used to treat cardiac conditions. This study …
FSHR ablation induces depression-like behaviors
W Bi, S Shao, Z Li, Y Ruan, S Luan, Z Dong… - Acta Pharmacologica …, 2020 - nature.com
Alteration in reproductive hormones profile is associated with the increasing risk of
menopausal depression in women. Serum follicle-stimulating hormone (FSH) level is …
menopausal depression in women. Serum follicle-stimulating hormone (FSH) level is …
[HTML][HTML] Elevated Expression of HSP72 in the Prefrontal Cortex and Hippocampus of Rats Subjected to Chronic Mild Stress and Treated with Imipramine
A Bielawski, A Zelek-Molik, K Rafa-Zabłocka… - International Journal of …, 2023 - mdpi.com
The HSP70 and HSP90 family members belong to molecular chaperones that exhibit
protective functions during the cellular response to stressful agents. We investigated …
protective functions during the cellular response to stressful agents. We investigated …
Hypothalamic insulin and glucagon-like peptide-1 levels in an animal model of depression and their effect on corticotropin-releasing hormone promoter gene activity …
J Detka, J Ślusarczyk, A Kurek, M Kucharczyk… - Pharmacological …, 2019 - Elsevier
Background In depression, excessive glucocorticoid action may cause maladaptive brain
changes, including in the pathways controlling energy metabolism. Insulin and glucagon …
changes, including in the pathways controlling energy metabolism. Insulin and glucagon …
Rewarding and Antidepressant Properties of Ketamine and Ethanol: Effects on the Brain-Derived Neurotrophic Factor and TrkB and p75NTR Receptors
MB Contó, RM Pautassi, R Camarini - Neuroscience, 2022 - Elsevier
There is a high level of comorbidity between depression and alcohol use disorder.
Subanesthetic doses of ketamine induce short-acting and enduring antidepressant effects …
Subanesthetic doses of ketamine induce short-acting and enduring antidepressant effects …
Prenatal Dexamethasone Exposure in Male Rats Alters Gene Expression Patterns of Epigenetic Enzymes in Hippocampus and Cortex
Objective: This study aimed to examine the effects of prenatal stress (PS) induced by
dexamethasone exposure on gene expression levels of epigenetic enzymes in …
dexamethasone exposure on gene expression levels of epigenetic enzymes in …