HIV-1 Vpr modulates macrophage metabolic pathways: a SILAC-based quantitative analysis
Human immunodeficiency virus type 1 encoded viral protein Vpr is essential for infection of
macrophages by HIV-1. Furthermore, these macrophages are resistant to cell death and are …
macrophages by HIV-1. Furthermore, these macrophages are resistant to cell death and are …
Macrophage derived cystatin B/cathepsin B in HIV replication and neuropathogenesis
L E. Rivera, K Colon, Y M. Cantres-Rosario… - Current HIV …, 2014 - benthamdirect.com
Mononuclear phagocytes including monocytes and macrophages, are important defense
components of innate immunity, but can be detrimental in HIV-1 infection by serving as the …
components of innate immunity, but can be detrimental in HIV-1 infection by serving as the …
Proteomics, biomarkers, and HIV‐1: A current perspective
MR Donnelly, P Ciborowski - PROTEOMICS–Clinical …, 2016 - Wiley Online Library
Despite more than three decades of extensive research, HIV‐1 infection although well
controlled with cART, remains incurable. Multifactorial complexity of the viral life‐cycle poses …
controlled with cART, remains incurable. Multifactorial complexity of the viral life‐cycle poses …
Long-term inhibition of HIV-1 replication with RNA interference against cellular co-factors
JJM Eekels, D Geerts, RE Jeeninga, B Berkhout - Antiviral research, 2011 - Elsevier
In this study we tested whether HIV-1 replication could be inhibited by stable RNAi-mediated
knockdown of cellular co-factors. Cell lines capable of expressing shRNAs against 30 …
knockdown of cellular co-factors. Cell lines capable of expressing shRNAs against 30 …
Multi‐analyte profile analysis of plasma immune proteins: altered expression of peripheral immune factors is associated with neuropsychiatric symptom severity in …
M Huckans, BE Fuller, H Olavarria… - Brain and …, 2014 - Wiley Online Library
Background The purpose of this study was to characterize hepatitis C virus (HCV)‐
associated differences in the expression of 47 inflammatory factors and to evaluate the …
associated differences in the expression of 47 inflammatory factors and to evaluate the …
Dysregulation of macrophage-secreted cathepsin B contributes to HIV-1-linked neuronal apoptosis
EJ Rodriguez-Franco, YM Cantres-Rosario… - PloS one, 2012 - journals.plos.org
Chronic HIV infection leads to the development of cognitive impairments, designated as HIV-
associated neurocognitive disorders (HAND). The secretion of soluble neurotoxic factors by …
associated neurocognitive disorders (HAND). The secretion of soluble neurotoxic factors by …
HIV infection enhances TRAIL-induced cell death in macrophage by down-regulating decoy receptor expression and generation of reactive oxygen species
DM Zhu, J Shi, S Liu, Y Liu, D Zheng - PloS one, 2011 - journals.plos.org
Background Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) could induce
apoptosis of HIV-1-infected monocyte-derived macrophage (MDM), but the molecular …
apoptosis of HIV-1-infected monocyte-derived macrophage (MDM), but the molecular …
Proteomic analysis of saliva in HIV-positive heroin addicts reveals proteins correlated with cognition
SS Dominy, JN Brown, MI Ryder, M Gritsenko… - PloS one, 2014 - journals.plos.org
The prevalence of HIV-associated neurocognitive disorders (HAND) remains high despite
effective antiretroviral therapies. Multiple etiologies have been proposed over the last …
effective antiretroviral therapies. Multiple etiologies have been proposed over the last …
Unique and differential protein signatures within the mononuclear cells of HIV-1 and HCV mono-infected and co-infected patients
NM Boukli, V Shetty, L Cubano, M Ricaurte… - Clinical proteomics, 2012 - Springer
Background Pathogenesis of liver damage in patients with HIV and HCV co-infection is
complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is …
complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is …
Proteomics to study macrophage response to viral infection
TA Nyman, S Matikainen - Journal of proteomics, 2018 - Elsevier
Viral infections are a major burden to human and animal health. Immune response against
viruses consists of innate and adaptive immunity which are both critical for the eradication of …
viruses consists of innate and adaptive immunity which are both critical for the eradication of …