Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …

Acute kidney injury (AKI) is a prevalent pathological condition that is characterized by a
precipitous decline in renal function. In recent years, a growing body of studies have …

Background: Myocardial ischemia-reperfusion (I/R) injury causes cardiac dysfunction to
myocardial cell loss and fibrosis. Prevention of cell death is important to protect cardiac …

Ischemia reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The role of
N6-methyladenosine (m6A) modification in AKI remains unclear. Here, we characterize the …

Neutrophils, as the first defenders against external microbes and stimuli, are highly active
and finely regulated innate immune cells. Emerging evidence has challenged the …

Pyroptosis is a novel inflammatory form of regulated cell death (RCD), characterized by cell
swelling, membrane rupture, and pro-inflammatory effects. It is recognized as a potent …

The ketogenic diet (KD) has been used as a treatment for epilepsy since the 1920s, and its
role in the prevention of many other diseases is now being considered. In recent years, there …

Estimated glomerular filtration rate (eGFR) impacts the concentration of plasma biomarkers
confounding biomarker association studies of eGFR with reverse causation. To identify …

Colorectal cancer exhibits dynamic cellular and genetic heterogeneity during progression
from precursor lesions toward malignancy. Analysis of spatial multi-omic data from 31 …

Inflammation is the major contributor to the mechanisms of acute kidney injury due to renal
ischemia–reperfusion injury (IRI). Trans-cinnamaldehyde (TCA) is a main bioactive …