Structure and function of IP3 receptors
Inositol 1, 4, 5-trisphosphate receptors (IP3Rs), by releasing Ca2+ from the endoplasmic
reticulum (ER) of animal cells, allow Ca2+ to be redistributed from the ER to the cytosol or …
reticulum (ER) of animal cells, allow Ca2+ to be redistributed from the ER to the cytosol or …
Inositol 1, 4, 5-trisphosphate receptors in cardiomyocyte physiology and disease
K Demydenko, S Ekhteraei-Tousi… - … Transactions of the …, 2022 - royalsocietypublishing.org
The contraction of cardiac muscle underlying the pumping action of the heart is mediated by
the process of excitation-contraction coupling (ECC). While triggered by Ca2+ entry across …
the process of excitation-contraction coupling (ECC). While triggered by Ca2+ entry across …
All three IP3 receptor subtypes generate Ca2+ puffs, the universal building blocks of IP3-evoked Ca2+ signals
S Mataragka, CW Taylor - Journal of cell science, 2018 - journals.biologists.com
All three subtypes of inositol 1, 4, 5-trisphosphate receptor (IP3R) are intracellular Ca2+
channels that are co-regulated by IP3 and Ca2+. This allows IP3Rs to evoke regenerative …
channels that are co-regulated by IP3 and Ca2+. This allows IP3Rs to evoke regenerative …
GPN does not release lysosomal Ca2+ but evokes Ca2+ release from the ER by increasing the cytosolic pH independently of cathepsin C
P Atakpa, LM van Marrewijk… - Journal of cell …, 2019 - journals.biologists.com
The dipeptide glycyl-l-phenylalanine 2-naphthylamide (GPN) is widely used to perturb
lysosomes because its cleavage by the lysosomal enzyme cathepsin C is proposed to …
lysosomes because its cleavage by the lysosomal enzyme cathepsin C is proposed to …
Endogenous signalling pathways and caged IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites
MV Keebler, CW Taylor - Journal of Cell Science, 2017 - journals.biologists.com
The building blocks of intracellular Ca2+ signals evoked by inositol 1, 4, 5-trisphosphate
receptors (IP3Rs) are Ca2+ puffs, transient focal increases in Ca2+ concentration that reflect …
receptors (IP3Rs) are Ca2+ puffs, transient focal increases in Ca2+ concentration that reflect …
CREB regulates the expression of type 1 inositol 1, 4, 5-trisphosphate receptors
V Arige, LE Terry, S Malik, TR Knebel… - Journal of Cell …, 2021 - journals.biologists.com
ABSTRACT Inositol 1, 4, 5-trisphosphate (IP3) receptors (IP3Rs) play a central role in
regulating intracellular Ca2+ signals in response to a variety of internal and external cues …
regulating intracellular Ca2+ signals in response to a variety of internal and external cues …