In silico T cell epitope identification for SARS-CoV-2: Progress and perspectives
Growing evidence suggests that T cells may play a critical role in combating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, COVID-19 vaccines that can …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Hence, COVID-19 vaccines that can …
Current and prospective computational approaches and challenges for developing COVID-19 vaccines
Abstract SARS-CoV-2, which causes COVID-19, was first identified in humans in late 2019
and is a coronavirus which is zoonotic in origin. As it spread around the world there has …
and is a coronavirus which is zoonotic in origin. As it spread around the world there has …
[HTML][HTML] Epitope-based chimeric peptide vaccine design against S, M and E proteins of SARS-CoV-2, the etiologic agent of COVID-19 pandemic: an in silico approach
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the
ongoing pandemic of coronavirus disease 2019 (COVID-19), a public health emergency of …
ongoing pandemic of coronavirus disease 2019 (COVID-19), a public health emergency of …
Computationally optimized SARS-CoV-2 MHC class I and II vaccine formulations predicted to target human haplotype distributions
We present a combinatorial machine learning method to evaluate and optimize peptide
vaccine formulations for SARS-CoV-2. Our approach optimizes the presentation likelihood of …
vaccine formulations for SARS-CoV-2. Our approach optimizes the presentation likelihood of …
In silico designing of a multi-epitope vaccine against Burkholderia pseudomallei: Reverse vaccinology and immunoinformatics
M Shahab, C Hayat, R Sikandar, G Zheng… - Journal of Genetic …, 2022 - Elsevier
Background Burkholderia pseudomallei is an infectious agent causing severe disease
melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei …
melioidosis resulting in pneumonia, fever, and acute septicemia in humans. B. pseudomallei …
[HTML][HTML] Spike protein-based epitopes predicted against SARS-CoV-2 through literature mining
W Li, L Li, T Sun, Y He, G Liu, Z Xiao, Y Fan… - Medicine in novel …, 2020 - Elsevier
Background With the diffusion of SARS-CoV-2 around the world, human health is being
threatened. As there is no effective vaccine yet, the development of the vaccine is urgently in …
threatened. As there is no effective vaccine yet, the development of the vaccine is urgently in …
Monitoring specific IgM and IgG production among severe COVID-19 patients using qualitative and quantitative immunodiagnostic assays: a retrospective cohort study
JA Al-Mughales, TJ Al-Mughales… - Frontiers in …, 2021 - frontiersin.org
The purpose of this study is to monitor specific anti-severe acute respiratory syndrome
coronavirus 2 (anti-SARS-CoV-2) IgG and IgM antibody production in patients with severe …
coronavirus 2 (anti-SARS-CoV-2) IgG and IgM antibody production in patients with severe …
Combination of highly antigenic nucleoproteins to inaugurate a cross-reactive next generation vaccine candidate against Arenaviridae family
Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and
South American regions. To date, there is no FDA-approved licensed vaccine against …
South American regions. To date, there is no FDA-approved licensed vaccine against …
Immunology to Immunotherapeutics of SARS-CoV-2: Identification of Immunogenic Epitopes for Vaccine Development
The emergence of COVID19 pandemic caused by SARS-CoV-2 virus has created a global
public health and socio-economic crisis. Immunoinformatics-based approaches to …
public health and socio-economic crisis. Immunoinformatics-based approaches to …
BCEDB: a linear B-cell epitopes database for SARS-CoV-2
C Tai, H Li, J Zhang - Database, 2023 - academic.oup.com
Abstract The 2019 Novel Coronavirus (SARS-CoV-2) has infected millions of people
worldwide and caused millions of deaths. The virus has gone numerous mutations to …
worldwide and caused millions of deaths. The virus has gone numerous mutations to …