In recent years, research on ions and ionic interactions in solution has become a leading
scientific direction, and this advance has been especially pronounced in the field of ionic …

Abstract Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …

Abstract Chagas Disease and Leishmaniasis are neglected parasitic diseases that
constitute a major public health problem. In the search for new therapeutic alternatives for …

Cutaneous leishmaniasis is one of the diseases that severely affects human skin. Nanogels
are the well-known formulation for topical drug delivery due to easy usage, high loading …

In this study, we report the synthesis and evaluation of in vitro and in vivo antitrypanosomal
activity of styrylquinoline-like compounds (SQ) 3a-h. Synthesis was carried out by using …

In the last decade, the World Health Organization has driven the development of drugs for
topical use in patients with cutaneous leishmaniasis (CL), the most prevalent clinical form of …

As the impact of aromatic rings and fluorine substituents in commercial drugs is attributed to
their electronic distribution and structure rigidity that determine metabolic stability and …

Antimonials are used as chemotherapy for leishmaniasis, but have limited results due to
their toxicity and broad resistance already acquired by the parasites. Nanotechnology offers …

Abstract The N-iodomethyl-N, N-Dimethyl-N-(6, 6-diphenylhex-5-en-1-yl) ammonium iodide
(C6I) is a new chemical entity (NCE) with demonstrated in vitro and in vivo antileishmanial …

A polyurethane artificial meniscus material containing a POSS capping agent was prepared
by a solvent-melt method, and in vitro properties were studied. Based on cell culture, its …