It is estimated that more than 339 million people worldwide suffer from asthma. The leading
cause of asthma development is the breakdown of immune tolerance to inhaled allergens …

There have been many attempts to identify common biophysical properties which
differentiate allergens from their non-immunogenic counterparts. This review will focus on …

Anaphylaxis is a systemic acute hypersensitivity reaction that is considered to depend on
allergen-specific immunoglobulin E (IgE) antibodies and histamine release by mast cells …

Rationale: Sensitization to Fel d 1 (Felis domesticus allergen 1) contributes to persistent
allergic rhinitis and asthma. Existing treatment options for cat allergy, including allergen …

Background Urinary schistosomiasis, the result of infection by Schistosoma haematobium
(Sh), remains a major global health concern. A schistosome vaccine could represent a …

Among the four immunoglobulin G (IgG) subclasses, IgG4 is the least represented in serum
of a healthy human and it is considered an “odd” antibody. The IgG4 antibody has unique …

Background Peanut allergy is a type‐I hypersensitivity immune reaction mediated by the
binding of peanut allergens to IgE‐FcεRI complexes on mast cells and basophils and by …

Shellfish allergy caused by undesirable immunological responses upon ingestion of
crustaceans and mollusks is a common cause of food allergy, especially in the Asia-Pacific …

Basophils are circulating cells that are associated quite exclusively with allergy response
and hypersensitivity reactions but their role in the immune network might be much more …

Pemphigoid diseases are autoimmune chronic inflammatory skin diseases, which are
characterized by blistering of the skin and/or mucous membranes, and circulating and tissue …