Adiponectin as link factor between adipose tissue and cancer
Adipose tissue is a key regulator of energy balance playing an active role in lipid storage as
well as in synthesizing several hormones directly involved in the pathogenesis of obesity …
well as in synthesizing several hormones directly involved in the pathogenesis of obesity …
PI3K/PTEN/AKT signaling pathways in germ cell development and their involvement in germ cell tumors and ovarian dysfunctions
M De Felici, FG Klinger - International Journal of Molecular Sciences, 2021 - mdpi.com
Several studies indicate that the PI3K/PTEN/AKT signaling pathways are critical regulators
of ovarian function including the formation of the germ cell precursors, termed primordial …
of ovarian function including the formation of the germ cell precursors, termed primordial …
MiR-503 modulates epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by targeting PI3K p85 and is sponged by lncRNA MALAT1
W Yan, Q Wu, W Yao, Y Li, Y Liu, J Yuan, R Han… - Scientific Reports, 2017 - nature.com
Silicosis is a kind of chronic, progressive and incurable lung fibrotic diseases with largely
unknown and complex pathogenesis and molecular mechanisms. Mounting evidence …
unknown and complex pathogenesis and molecular mechanisms. Mounting evidence …
The role of oxidative stress and hormones in controlling obesity
M Di Domenico, F Pinto, L Quagliuolo… - Frontiers in …, 2019 - frontiersin.org
The accumulation of adipose tissue in the body occurs because the energy introduced with
food and drink exceeds that expense, but to understand why this imbalance is established …
food and drink exceeds that expense, but to understand why this imbalance is established …
The crosstalk between prostate cancer and microbiota inflammation: nutraceutical products are useful to balance this interplay?
The human microbiota shows pivotal roles in urologic health and disease. Emerging studies
indicate that gut and urinary microbiomes can impact several urological diseases, both …
indicate that gut and urinary microbiomes can impact several urological diseases, both …
How glutamate is managed by the blood–brain barrier
RA Hawkins, JR Viña - Biology, 2016 - mdpi.com
A facilitative transport system exists on the blood–brain barrier (BBB) that has been tacitly
assumed to be a path for glutamate entry to the brain. However, glutamate is a non-essential …
assumed to be a path for glutamate entry to the brain. However, glutamate is a non-essential …
PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction
Cyclic nucleotide phosphodiesterase 1C (PDE1C) represents a major phosphodiesterase
activity in human myocardium, but its function in the heart remains unknown. Using genetic …
activity in human myocardium, but its function in the heart remains unknown. Using genetic …
The role of curcumin in prostate cancer cells and derived spheroids
Simple Summary In recent years, considerable efforts have been made to discover new
compounds useful for prostate cancer (PC) therapy and related clinical management …
compounds useful for prostate cancer (PC) therapy and related clinical management …
Early modulation of circulating microRNAs levels in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapy
S Di Cosimo, V Appierto, S Pizzamiglio… - International journal of …, 2020 - mdpi.com
Circulating microRNA (ct-miRNAs) are able to identify patients with differential response to
HER2-targeted therapy. However, their dynamics are largely unknown. We assessed 752 …
HER2-targeted therapy. However, their dynamics are largely unknown. We assessed 752 …
Network-based integration of disparate omic data to identify" silent players" in cancer
Development of high-throughput monitoring technologies enables interrogation of cancer
samples at various levels of cellular activity. Capitalizing on these developments, various …
samples at various levels of cellular activity. Capitalizing on these developments, various …