Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications
Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …
Biomarkers in autism
AAS Goldani, SR Downs, F Widjaja, B Lawton… - Frontiers in …, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are complex, heterogeneous disorders caused by an
interaction between genetic vulnerability and environmental factors. In an effort to better …
interaction between genetic vulnerability and environmental factors. In an effort to better …
Hippocampal plasticity in response to exercise in schizophrenia
FG Pajonk, T Wobrock, O Gruber… - Archives of general …, 2010 - jamanetwork.com
Context Hippocampal volume is lower than expected in patients with schizophrenia;
however, whether this represents a fixed deficit is uncertain. Exercise is a stimulus to …
however, whether this represents a fixed deficit is uncertain. Exercise is a stimulus to …
Antioxidants as potential therapeutics for neuropsychiatric disorders
Oxidative stress has been implicated in the pathophysiology of many neuropsychiatric
disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and …
disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and …
Oxidative stress in schizophrenia
M Boskovic, T Vovk, B Kores Plesnicar… - Current …, 2011 - ingentaconnect.com
Increasing evidence indicates that oxidative damage exists in schizophrenia. Available
literature about possible mechanisms of oxidative stress induction was reviewed …
literature about possible mechanisms of oxidative stress induction was reviewed …
Mitochondrial oxidative phosphorylation system (OXPHOS) deficits in schizophrenia: possible interactions with cellular processes
O Bergman, D Ben-Shachar - The Canadian Journal of …, 2016 - journals.sagepub.com
Mitochondria are key players in the generation and regulation of cellular bioenergetics,
producing the majority of adenosine triphosphate molecules by the oxidative …
producing the majority of adenosine triphosphate molecules by the oxidative …
Antioxidant and anti-inflammatory effects of carotenoids in mood disorders: an overview
P Rasmus, E Kozłowska - Antioxidants, 2023 - mdpi.com
Depression has a multifactorial etiology comprising family history and unemployment. This
review aims to summarize the evidence available for the antioxidant and anti-inflammatory …
review aims to summarize the evidence available for the antioxidant and anti-inflammatory …
Comparative pharmacology of risperidone and paliperidone
M Corena-McLeod - Drugs in R&D, 2015 - Springer
Antipsychotics, risperidone, and risperidone's active metabolite, paliperidone (9-
hydroxyrisperidone), are related molecules used for the treatment of schizophrenia and …
hydroxyrisperidone), are related molecules used for the treatment of schizophrenia and …
Mechanistic review of drug-induced steatohepatitis
JD Schumacher, GL Guo - Toxicology and applied pharmacology, 2015 - Elsevier
Drug-induced steatohepatitis is a rare form of liver injury known to be caused by only a
handful of compounds. These compounds stimulate the development of steatohepatitis …
handful of compounds. These compounds stimulate the development of steatohepatitis …
Atypical antipsychotics-induced metabolic syndrome and nonalcoholic fatty liver disease: a critical review
H Xu, X Zhuang - Neuropsychiatric disease and treatment, 2019 - Taylor & Francis
The atypical antipsychotics (AAPs) have been used as first-line drugs in psychiatric practice
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …