Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications

A Rajasekaran, G Venkatasubramanian, M Berk… - Neuroscience & …, 2015 - Elsevier
Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

Biomarkers in autism

AAS Goldani, SR Downs, F Widjaja, B Lawton… - Frontiers in …, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are complex, heterogeneous disorders caused by an
interaction between genetic vulnerability and environmental factors. In an effort to better …

Hippocampal plasticity in response to exercise in schizophrenia

FG Pajonk, T Wobrock, O Gruber… - Archives of general …, 2010 - jamanetwork.com
Context Hippocampal volume is lower than expected in patients with schizophrenia;
however, whether this represents a fixed deficit is uncertain. Exercise is a stimulus to …

Antioxidants as potential therapeutics for neuropsychiatric disorders

CD Pandya, KR Howell, A Pillai - Progress in Neuro-Psychopharmacology …, 2013 - Elsevier
Oxidative stress has been implicated in the pathophysiology of many neuropsychiatric
disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and …

Oxidative stress in schizophrenia

M Boskovic, T Vovk, B Kores Plesnicar… - Current …, 2011 - ingentaconnect.com
Increasing evidence indicates that oxidative damage exists in schizophrenia. Available
literature about possible mechanisms of oxidative stress induction was reviewed …

Mitochondrial oxidative phosphorylation system (OXPHOS) deficits in schizophrenia: possible interactions with cellular processes

O Bergman, D Ben-Shachar - The Canadian Journal of …, 2016 - journals.sagepub.com
Mitochondria are key players in the generation and regulation of cellular bioenergetics,
producing the majority of adenosine triphosphate molecules by the oxidative …

Antioxidant and anti-inflammatory effects of carotenoids in mood disorders: an overview

P Rasmus, E Kozłowska - Antioxidants, 2023 - mdpi.com
Depression has a multifactorial etiology comprising family history and unemployment. This
review aims to summarize the evidence available for the antioxidant and anti-inflammatory …

Comparative pharmacology of risperidone and paliperidone

M Corena-McLeod - Drugs in R&D, 2015 - Springer
Antipsychotics, risperidone, and risperidone's active metabolite, paliperidone (9-
hydroxyrisperidone), are related molecules used for the treatment of schizophrenia and …

Mechanistic review of drug-induced steatohepatitis

JD Schumacher, GL Guo - Toxicology and applied pharmacology, 2015 - Elsevier
Drug-induced steatohepatitis is a rare form of liver injury known to be caused by only a
handful of compounds. These compounds stimulate the development of steatohepatitis …

Atypical antipsychotics-induced metabolic syndrome and nonalcoholic fatty liver disease: a critical review

H Xu, X Zhuang - Neuropsychiatric disease and treatment, 2019 - Taylor & Francis
The atypical antipsychotics (AAPs) have been used as first-line drugs in psychiatric practice
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …