Synaptic control of motoneuronal excitability
Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …
brain, is produced when skeletal muscles contract and relax in response to patterns of action …
[HTML][HTML] Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit
We have characterized the phosphorylation of the glutamate receptor subunit GluR1, using
biochemical and electrophysiological techniques. GluR1 is phosphorylated on multiple sites …
biochemical and electrophysiological techniques. GluR1 is phosphorylated on multiple sites …
NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus
Brief bath application of N-methyl-D-aspartate (NMDA) to hippocampal slices produces long-
term synaptic depression (LTD) in CA1 that is (1) sensitive to postnatal age,(2) saturable,(3) …
term synaptic depression (LTD) in CA1 that is (1) sensitive to postnatal age,(2) saturable,(3) …
[图书][B] Perceptual neuroscience: the cerebral cortex
VB Mountcastle - 1998 - books.google.com
The cerebral cortex, occupying over 70 percent of our brain mass, is key to any
understanding of the workings--and disorders--of the human brain. offering a …
understanding of the workings--and disorders--of the human brain. offering a …
Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor
FJS Lee, S Xue, L Pei, B Vukusic, N Chéry, Y Wang… - Cell, 2002 - cell.com
Dopamine D1-like receptors, composed of D1 and D5 receptors, have been documented to
modulate glutamate-mediated fast excitatory synaptic neurotransmission. Here, we report …
modulate glutamate-mediated fast excitatory synaptic neurotransmission. Here, we report …
Regulation of NMDA receptors by phosphorylation
BS Chen, KW Roche - Neuropharmacology, 2007 - Elsevier
N-Methyl-d-aspartate (NMDA) receptors are critical for neuronal development and synaptic
plasticity. The molecular mechanisms underlying the synaptic localization and functional …
plasticity. The molecular mechanisms underlying the synaptic localization and functional …
Phosphorylation of the α-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II
Modulation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid (AMPA) receptors in
the brain by protein phosphorylation may play a crucial role in the regulation of synaptic …
the brain by protein phosphorylation may play a crucial role in the regulation of synaptic …
[HTML][HTML] Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit
MD Ehlers, S Zhang, JP Bernhardt, RL Huganir - Cell, 1996 - cell.com
Abstract NMDA (N-methyl-D-aspartate) receptors are excitatory neurotransmitter receptors in
the brain critical for synaptic plasticity and neuronal development. These receptors are Ca …
the brain critical for synaptic plasticity and neuronal development. These receptors are Ca …
Clustering of AMPA receptors by the synaptic PDZ domain–containing protein PICK1
Synaptic clustering of neurotransmitter receptors is crucial for efficient signal transduction
and integration in neurons. PDZ domain–containing proteins such as PSD-95/SAP90 …
and integration in neurons. PDZ domain–containing proteins such as PSD-95/SAP90 …
Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific …
WG Tingley, MD Ehlers, K Kameyama… - Journal of Biological …, 1997 - ASBMB
Modulation of N-methyl-D-aspartate receptors in the brain by protein phosphorylation may
play a central role in the regulation of synaptic plasticity. To examine the phosphorylation of …
play a central role in the regulation of synaptic plasticity. To examine the phosphorylation of …