Synaptic control of motoneuronal excitability

JC Rekling, GD Funk, DA Bayliss… - Physiological …, 2000 - journals.physiology.org
Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …

[HTML][HTML] Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit

KW Roche, RJ O'Brien, AL Mammen, J Bernhardt… - Neuron, 1996 - cell.com
We have characterized the phosphorylation of the glutamate receptor subunit GluR1, using
biochemical and electrophysiological techniques. GluR1 is phosphorylated on multiple sites …

NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus

HK Lee, K Kameyama, RL Huganir, MF Bear - Neuron, 1998 - cell.com
Brief bath application of N-methyl-D-aspartate (NMDA) to hippocampal slices produces long-
term synaptic depression (LTD) in CA1 that is (1) sensitive to postnatal age,(2) saturable,(3) …

[图书][B] Perceptual neuroscience: the cerebral cortex

VB Mountcastle - 1998 - books.google.com
The cerebral cortex, occupying over 70 percent of our brain mass, is key to any
understanding of the workings--and disorders--of the human brain. offering a …

Dual regulation of NMDA receptor functions by direct protein-protein interactions with the dopamine D1 receptor

FJS Lee, S Xue, L Pei, B Vukusic, N Chéry, Y Wang… - Cell, 2002 - cell.com
Dopamine D1-like receptors, composed of D1 and D5 receptors, have been documented to
modulate glutamate-mediated fast excitatory synaptic neurotransmission. Here, we report …

Regulation of NMDA receptors by phosphorylation

BS Chen, KW Roche - Neuropharmacology, 2007 - Elsevier
N-Methyl-d-aspartate (NMDA) receptors are critical for neuronal development and synaptic
plasticity. The molecular mechanisms underlying the synaptic localization and functional …

Phosphorylation of the α-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II

AL Mammen, K Kameyama, KW Roche… - Journal of Biological …, 1997 - ASBMB
Modulation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid (AMPA) receptors in
the brain by protein phosphorylation may play a crucial role in the regulation of synaptic …

[HTML][HTML] Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit

MD Ehlers, S Zhang, JP Bernhardt, RL Huganir - Cell, 1996 - cell.com
Abstract NMDA (N-methyl-D-aspartate) receptors are excitatory neurotransmitter receptors in
the brain critical for synaptic plasticity and neuronal development. These receptors are Ca …

Clustering of AMPA receptors by the synaptic PDZ domain–containing protein PICK1

J Xia, X Zhang, J Staudinger, RL Huganir - Neuron, 1999 - cell.com
Synaptic clustering of neurotransmitter receptors is crucial for efficient signal transduction
and integration in neurons. PDZ domain–containing proteins such as PSD-95/SAP90 …

Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific …

WG Tingley, MD Ehlers, K Kameyama… - Journal of Biological …, 1997 - ASBMB
Modulation of N-methyl-D-aspartate receptors in the brain by protein phosphorylation may
play a central role in the regulation of synaptic plasticity. To examine the phosphorylation of …