Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

Curcumin is a natural polyphenol with evidence of antioxidant, anti-inflammatory and
neuroprotective properties. Recent evidence also suggests that curcumin increases …

Given the ability of akebia saponin D (ASD) to protect various types of stem cells, in the
present study, we hypothesized that ASD could promote the proliferation, differentiation, and …

Alzheimer's disease (AD) is the most common form of dementia and seriously affects the
quality of life of the elderly. Neurodegeneration is closely related to hippocampal dysfunction …

Processes such as aberrant redox signaling and chronic low-grade systemic inflammation
have been reported to modulate age-associated pathologies such as cognitive impairment …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

Adult neurogenesis was one of the most important discoveries of the last century, helping us
to better understand brain function. Researchers recently discovered that microglia play an …

Alzheimer's disease (AD) is of multifactorial origin, and still presents several gaps regarding
its development and progression. Disorders of the cholinergic system are well known to be …