Progress in microRNA delivery
Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …
regulation of gene expression by several mechanisms. Activity is primarily through binding …
Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors
H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …
MicroRNA-mediated conversion of human fibroblasts to neurons
Neurogenic transcription factors and evolutionarily conserved signalling pathways have
been found to be instrumental in the formation of neurons,. However, the instructive role of …
been found to be instrumental in the formation of neurons,. However, the instructive role of …
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
Evolutionary expansion of the human neocortex reflects increased amplification of basal
progenitors in the subventricular zone, producing more neurons during fetal corticogenesis …
progenitors in the subventricular zone, producing more neurons during fetal corticogenesis …
Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development
MicroRNAs (miRNAs) regulate many cellular events during brain development by interacting
with hundreds of mRNA transcripts. However, miRNAs operate nonuniformly upon the …
with hundreds of mRNA transcripts. However, miRNAs operate nonuniformly upon the …
A framework for understanding the roles of miRNAs in animal development
C Alberti, L Cochella - Development, 2017 - journals.biologists.com
MicroRNAs (miRNAs) contribute to the progressive changes in gene expression that occur
during development. The combined loss of all miRNAs results in embryonic lethality in all …
during development. The combined loss of all miRNAs results in embryonic lethality in all …
Emerging roles of miRNAs in brain development and perinatal brain injury
KHT Cho, B Xu, C Blenkiron, M Fraser - Frontiers in physiology, 2019 - frontiersin.org
In human beings the immature brain is highly plastic and depending on the stage of
gestation is particularly vulnerable to a range of insults that if sufficiently severe, can result in …
gestation is particularly vulnerable to a range of insults that if sufficiently severe, can result in …
[HTML][HTML] MicroRNAs: Small molecules with big roles in neurodevelopment and diseases
E Sun, Y Shi - Experimental neurology, 2015 - Elsevier
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that play important
roles in the development and functions of the brain. Extensive studies have revealed critical …
roles in the development and functions of the brain. Extensive studies have revealed critical …
Transcriptome-wide discovery of microRNA binding sites in human brain
The orchestration of brain function requires complex gene regulatory networks that are
modulated, in part, by microRNAs (miRNAs). These noncoding RNAs associate with …
modulated, in part, by microRNAs (miRNAs). These noncoding RNAs associate with …
MicroRNA profiling in subventricular zone after stroke: MiR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway
XS Liu, M Chopp, RL Zhang, T Tao, XL Wang… - PloS one, 2011 - journals.plos.org
Background The Notch signaling pathway regulates adult neurogenesis under physiological
and pathophysiological conditions. MicroRNAs are small non-coding RNA molecules that …
and pathophysiological conditions. MicroRNAs are small non-coding RNA molecules that …