Understanding progressive multifocal leukoencephalopathy risk in multiple sclerosis patients treated with immunomodulatory therapies: a bird's eye view

EA Mills, Y Mao-Draayer - Frontiers in Immunology, 2018 - frontiersin.org
The increased use of newer potent immunomodulatory therapies for multiple sclerosis (MS),
including natalizumab, fingolimod, and dimethyl fumarate, has expanded the patient …

[HTML][HTML] Systematic review of the published data on the worldwide prevalence of John Cunningham virus in patients with multiple sclerosis and neuromyelitis optica

SPC Paz, L Branco, MA de Camargo Pereira… - Epidemiology and …, 2018 - ncbi.nlm.nih.gov
OBJECTIVES John Cunningham virus (JCV) is a polyoma virus that infects humans, mainly
in childhood or adolescence, and presents no symptomatic manifestations. JCV can cause …

Risk assessment of progressive multifocal leukoencephalopathy in multiple sclerosis patients during 1 year of ocrelizumab treatment

C Prezioso, A Grimaldi, D Landi, CG Nicoletti… - Viruses, 2021 - mdpi.com
Background: Progressive multifocal leukoencephalopathy (PML) caused by the JC virus is
the main limitation to the use of disease modifying therapies for treatment of multiple …

[PDF][PDF] High seroprevalence and index of anti-john-cunningham virus antibodies in korean patients with multiple sclerosis

SW Kim, TG Kim, J Oh, DY Kim… - Journal of Clinical …, 2019 - synapse.koreamed.org
Background and Purpose Neurological involvement in Behçet's disease [neuro-Behçet's
disease (NBD)] is uncommon, but it is worth investigating since it can cause substantial …

Anti-JCV antibody index seroconversion in Turkish multiple sclerosis patients treated with natalizumab

E Şahin, T Gündüz, AS Emekli, M Ercanoğlu… - Neurological …, 2024 - Springer
Background The anti-JCV antibody index is widely used to monitor multiple sclerosis (MS)
patients receiving natalizumab, as seroconversion is linked to an increased risk of …

Changes in anti-JCV antibody status in a large population of multiple sclerosis patients treated with natalizumab

E Sgarlata, CG Chisari, E D'Amico, E Millefiorini, F Patti - CNS drugs, 2020 - Springer
Introduction Natalizumab (NTZ) can be associated with an opportunistic infection,
progressive multifocal leukoencephalopathy (PML), caused by John Cunningham virus …

JC virus seroprevalence and JCVAb index in polish multiple sclerosis patients treated with immunomodulating or immunosuppressive therapies

R Bonek, W Guenter, R Jałowiński, A Karbicka… - Journal of Clinical …, 2021 - mdpi.com
The use of a highly-effective treatment for multiple sclerosis (MS) is associated with a severe
risk of developing complications, such as progressive multifocal leukoencephalopathy …

Incidence of seroconversion and sero-reversion in patients with multiple sclerosis (MS) who had been treated with natalizumab: A systematic review and meta …

A Azimi, S Hanaei, MA Sahraian… - Journal of Clinical …, 2020 - Elsevier
Background Natalizumab is a medication of choice for some patients with relapsing remitting
(RR) form of multiple sclerosis (MS). John Cunningham virus (JCV) antibody status is …

Longitudinal stability of JCV antibody index in Natalizumab treated people with multiple sclerosis

M Gaughan, M Gilligan, I Patterson, I McGurgan… - Multiple Sclerosis and …, 2022 - Elsevier
Objective The aim of this study was to evaluate the evolution of JCV index over time in
Natalizumab treated people with multiple sclerosis. Materials and Methods We …

A longitudinal study of JC virus serostatus stability among multiple sclerosis patients

R Alroughani, S Akhtar, S Ahmed… - Multiple sclerosis and …, 2018 - Elsevier
Abstract Background Anti-JC virus (JCV) antibody testing has been used increasingly to
stratify multiple sclerosis (MS) patients into different disease modifying therapies. Objectives …