Heme oxygenase-1: the “emerging molecule” has arrived
D Morse, AMK Choi - American journal of respiratory cell and …, 2002 - atsjournals.org
Organisms on our planet have evolved in an oxidizing environment that is intrinsically
inimical to life, and cells have been forced to devise means of protecting themselves. One of …
inimical to life, and cells have been forced to devise means of protecting themselves. One of …
Heme oxygenase-1 and carbon monoxide in pulmonary medicine
DJ Slebos, SW Ryter, AMK Choi - Respiratory Research, 2003 - Springer
Abstract Heme oxygenase-1 (HO-1), an inducible stress protein, confers cytoprotection
against oxidative stress in vitro and in vivo. In addition to its physiological role in heme …
against oxidative stress in vitro and in vivo. In addition to its physiological role in heme …
Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1
D Morse, SE Pischke, Z Zhou, RJ Davis… - Journal of Biological …, 2003 - ASBMB
The stress-inducible protein heme oxygenase-1 provides protection against oxidative stress
and modulates pro-inflammatory cytokines. As the sepsis syndrome results from the release …
and modulates pro-inflammatory cytokines. As the sepsis syndrome results from the release …
Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis
YT Ghebremariam, JP Cooke, W Gerhart… - Journal of translational …, 2015 - Springer
Background The beneficial outcome associated with the use of proton pump inhibitors (PPIs)
in idiopathic pulmonary fibrosis (IPF) has been reported in retrospective studies. To date, no …
in idiopathic pulmonary fibrosis (IPF) has been reported in retrospective studies. To date, no …
Oxidative stress in patients with non-complicated malaria
A Pabón, J Carmona, LC Burgos, S Blair - Clinical biochemistry, 2003 - Elsevier
Aim: To compare oxidative stress in adults with non-complicated malaria and healthy
controls. Methodology: We measured malondialdehyde (MDA), total antioxidant status …
controls. Methodology: We measured malondialdehyde (MDA), total antioxidant status …
Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis
G Paul, F Bataille, F Obermeier, J Bock… - Clinical & …, 2005 - academic.oup.com
Summary Haem-oxygenase-1 (HO-1) has been shown to exert anti-inflammatory, anti-
apoptotic and anti-proliferative effects. We investigated HO-1 expression in patients with …
apoptotic and anti-proliferative effects. We investigated HO-1 expression in patients with …
Heme oxygenases in pregnancy II: HO‐2 is downregulated in human pathologic pregnancies
AC Zenclussen, E Lim, S Knoeller… - American journal of …, 2003 - Wiley Online Library
Problem: We previously reported a diminished expression of the heme‐degrading enzymes
heme oxygenases (HO)‐1 and HO‐2 in decidua and placenta from mice undergoing Th1 …
heme oxygenases (HO)‐1 and HO‐2 in decidua and placenta from mice undergoing Th1 …
Redox regulation of lung inflammation by thioredoxin
T Nakamura, H Nakamura, T Hoshino… - Antioxidants & redox …, 2005 - liebertpub.com
The lungs are the richest in oxygen among the various organs of the body and are always
subject to harmful reactive oxygen species. Regulation of the reduction/oxidation (redox) …
subject to harmful reactive oxygen species. Regulation of the reduction/oxidation (redox) …
Over-expression of heme oxygenase-1 by adenoviral gene transfer improves pregnancy outcome in a murine model of abortion
ML Zenclussen, I Anegon, AZ Bertoja… - Journal of reproductive …, 2006 - Elsevier
Mammalian pregnancy is a complex phenomenon allowing the maternal immune system to
support its allogeneic fetus. Physiological pathways protecting the fetus from rejection are …
support its allogeneic fetus. Physiological pathways protecting the fetus from rejection are …
[PDF][PDF] The oxidative state of children with cyanotic and acyanotic congenital heart disease.
Objective: The type of congenital heart disease, early diagnosis, and treatment modality all
play an important role in the morbidity and mortality of these diseases. This study examined …
play an important role in the morbidity and mortality of these diseases. This study examined …