Sex differences in traumatic brain injury: what we know and what we should know

RP Gupte, WM Brooks, RR Vukas, JD Pierce… - Journal of …, 2019 - liebertpub.com
There is growing recognition of the problem of male bias in neuroscience research,
including in the field of traumatic brain injury (TBI) where fewer women than men are …

Repeated mild traumatic brain injury: potential mechanisms of damage

B Fehily, M Fitzgerald - Cell transplantation, 2017 - journals.sagepub.com
Mild traumatic brain injury (mTBI) represents a significant public healthcare concern,
accounting for the majority of all head injuries. While symptoms are generally transient …

Sex-related responses after traumatic brain injury: Considerations for preclinical modeling

CB Späni, DJ Braun, LJ Van Eldik - Frontiers in neuroendocrinology, 2018 - Elsevier
Traumatic brain injury (TBI) has historically been viewed as a primarily male problem, since
men are more likely to experience a TBI because of more frequent participation in activities …

The potential for animal models to provide insight into mild traumatic brain injury: translational challenges and strategies

SR Shultz, SJ McDonald, CV Haar, A Meconi… - Neuroscience & …, 2017 - Elsevier
Mild traumatic brain injury (mTBI) is a common health problem. There is tremendous
variability and heterogeneity in human mTBI, including mechanisms of injury, biomechanical …

The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: a status report

EH McNamara, AA Grillakis, LB Tucker… - Experimental neurology, 2020 - Elsevier
Closed-head traumatic brain injury (TBI) is a worldwide concern with increasing prevalence
and cost to society. Rotational acceleration is a primary mechanism in TBI that results from …

Considerations for experimental animal models of concussion, traumatic brain injury, and chronic traumatic encephalopathy—these matters matter

MW Wojnarowicz, AM Fisher, O Minaeva… - Frontiers in …, 2017 - frontiersin.org
Animal models of concussion, traumatic brain injury (TBI), and chronic traumatic
encephalopathy (CTE) are widely available and routinely deployed in laboratories around …

Public health impact of androgens

G Kanayama, MJ Kaufman… - Current Opinion in …, 2018 - journals.lww.com
Public health impact of androgens : Current Opinion in Endocrinology, Diabetes and Obesity
Public health impact of androgens : Current Opinion in Endocrinology, Diabetes and Obesity …

CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice

WH Cheng, KM Martens, A Bashir, H Cheung… - Alzheimer's research & …, 2019 - Springer
Background The annual incidence of traumatic brain injury (TBI) in the United States is over
2.5 million, with approximately 3–5 million people living with chronic sequelae. Compared …

Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis

A Bashir, ZA Abebe, KA McInnes, EB Button… - Experimental …, 2020 - Elsevier
Traumatic brain injury (TBI) is a leading cause of death and disability in modern societies.
Diffuse axonal and vascular injury are nearly universal consequences of mechanical energy …

The course and prognostic factors of cognitive outcomes after traumatic brain injury: A systematic review and meta-analysis

T Mollayeva, S Mollayeva, N Pacheco… - Neuroscience & …, 2019 - Elsevier
Despite indications that TBI may be a precursor of cognitive decline and subsequent
development of Alzheimer's disease, little is known about the time course of this relationship …