Salmonella enterica infections are common causes of bloodstream infection in low-resource
areas, where they may be difficult to distinguish from other febrile illnesses and may be …

Ciprofloxacin is a broad spectrum fluoroquinolone antibacterial agent. Since its introduction
in the 1980s, most Gram-negative bacteria have remained highly susceptible to this agent in …

The fluoroquinolones, a new class of potent orally absorbed antimicrobial agents, are
reviewed, considering structure, mechanisms of action and resistance, spectrum, variables …

Ciprofloxacin, considered a benchmark when comparing new fluoroquinolones, shares with
these agents a common mechanism of action: inhibition of DNA gyrase. While ciprofloxacin …

OBJECTIVES AND DESIGN:: To determine the most appropriate approach to antibiotic
therapy for osteomyelitis, the medical literature for articles published from 1968 to 2000 was …

The newer fluoroquinolones are a major advance in antimicrobial chemotherapy. They
inhibit the supercoiling activity of the DNA gyrase enzyme, thus exerting their antibacterial …

Salmonella remains a leading etiological agent in bacterial foodborne diseases. Although
human salmonellosis generally presents as a self-limiting episode of enterocolitis, the …

The 4-fluoroquinolones are a new class of antimicrobial agents that possess broad in vitro
antibacterial activity, including efficacy against enteric pathogens such as Salmonella …

Salmonellae have demonstrated an extraordinary capacity to adapt to a wide range of
ecologic niches and to the peculiarities of modern society, such as the mass production of …

Objective: To determine the efficacy of ciprofloxacin therapy in eradicating convalescent
fecal excretion of salmonellae after acute salmonellosis. Design: Randomized, placebo …