Background Extent of resection is considered to be a prognostic factor in neuro‐oncology.
Intraoperative imaging technologies are designed to help achieve this goal. It is not clear …

Background Extent of resection is believed to be a key prognostic factor in neuro‐oncology.
Image guided surgery uses a variety of tools or technologies to help achieve this goal. It is …

OBJECTIVE Balancing the benefits of extensive tumor resection with the consequence of
potential postoperative deficits remains a challenge in malignant astrocytoma surgery …

Background High grade glioma (HGG) is an aggressive form of brain cancer. Treatment of
HGG usually entails biopsy, or resection if safe, followed by radiotherapy. Temozolomide is …

Although a primary tenet of neurosurgical oncology is that survival can improve with greater
tumor resection, this principle must be tempered by the potential for functional loss following …

Background Multiple studies have identified the prognostic relevance of extent of resection
in the management of glioma. Different intraoperative technologies have emerged in recent …

Background Standard treatment for high grade glioma (HGG) usually entails surgery (either
biopsy or resection) followed by radiotherapy plus or minus temozolomide. Implanting …

Malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) which have a
combined incidence of 5–8/100,000 population, represent the most common primary central …

Glioblastoma multiforme (GBM) remains a challenging disease, as it is the most common
and deadly brain tumour in adults and has no curative solution and an overall short survival …

In the past 30 years, only one drug (temozolomide) has been found to modestly improve
survival in patients with glioblastoma. 1 This lack of progress is remarkable given the …