Backgrounds: Compared with previously published meta-analyses, this is the first study to
investigate the combined effects of glutathione-S-transferase polymorphisms (GSTM1 …

Background GSTM1 deletion was reported to be associated with CKD progression in cohort
studies. However, the results of case‒control studies were conflicting. The association …

Introduction An imbalance between reactive oxygen species (ROS) generation and the
defence mechanisms underlying the activity of antioxidant enzymes has been demonstrated …

Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disease that affects motor
neurons and promotes progressive muscle atrophy. It has a multifactorial etiology, where …

Cadmium (Cd) is a toxic metal which is harmful to humans and the environment. Cd levels
and adverse effects may be associated with genetic polymorphisms in genes involved in its …

This genetic association study included 150 hypertensive diabetic patients and 150
normotensives non-diabetic subjects. Glutathione S-transferases M1 and T1 …

Diabetic Nephropathy (DN) stands as a primary cause of end-stage renal disease and its
etiology remains unclear. Thus, this study aims to construct a genetic panel with potential …

Diabetes has become an emerging public health problem because of its serious
complications, and high mortality and morbidity rates. Among the most common …

Background Overproduction of reactive oxygen species as a result of hyperglycemia in
diabetes mellitus leads to microvascular complications. Glutathione S-transferases play …

The glutathione S-transferases superfamily (GSTs) act on the detoxification process of
xenobiotics and oxidative stress products. The relevance of gene-environment interactions …