Function of renal nerves in kidney physiology and pathophysiology

JW Osborn, R Tyshynsky… - Annual review of …, 2021 - annualreviews.org
Renal sympathetic (efferent) nerves play an important role in the regulation of renal function,
including glomerular filtration, sodium reabsorption, and renin release. The kidney is also …

Neural circuits underlying thirst and fluid homeostasis

CA Zimmerman, DE Leib, ZA Knight - Nature Reviews Neuroscience, 2017 - nature.com
Thirst motivates animals to find and consume water. More than 40 years ago, a set of
interconnected brain structures known as the lamina terminalis was shown to govern thirst …

[HTML][HTML] Warm-sensitive neurons that control body temperature

CL Tan, EK Cooke, DE Leib, YC Lin, GE Daly… - Cell, 2016 - cell.com
Thermoregulation is one of the most vital functions of the brain, but how temperature
information is converted into homeostatic responses remains unknown. Here, we use an …

[HTML][HTML] The blood-brain barrier in brain homeostasis and neurological diseases

N Weiss, F Miller, S Cazaubon, PO Couraud - Biochimica et Biophysica …, 2009 - Elsevier
Brain endothelial cells are unique among endothelial cells in that they express apical
junctional complexes, including tight junctions, which quite resemble epithelial tight …

Central mechanisms of osmosensation and systemic osmoregulation

CW Bourque - Nature Reviews Neuroscience, 2008 - nature.com
Systemic osmoregulation is a vital process whereby changes in plasma osmolality, detected
by osmoreceptors, modulate ingestive behaviour, sympathetic outflow and renal function to …

Thirst driving and suppressing signals encoded by distinct neural populations in the brain

Y Oka, M Ye, CS Zuker - Nature, 2015 - nature.com
Thirst is the basic instinct to drink water. Previously, it was shown that neurons in several
circumventricular organs of the hypothalamus are activated by thirst-inducing conditions …

The physiological regulation of thirst and fluid intake

MJ McKinley, AK Johnson - Physiology, 2004 - journals.physiology.org
Thirst is important for maintaining body fluid homeostasis and may arise from deficits in
either intracellular or extracellular fluid volume. Neural signals arising from osmotic and …

Sympathetic nervous system contributions to hypertension: updates and therapeutic relevance

LJ DeLalio, AF Sved, SD Stocker - Canadian Journal of Cardiology, 2020 - Elsevier
The sympathetic nervous system plays a pivotal role in the long-term regulation of arterial
blood pressure through the ability of the central nervous system to integrate neurohumoral …

Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ

T Matsuda, TY Hiyama, F Niimura, T Matsusaka… - Nature …, 2017 - nature.com
Body fluid conditions are continuously monitored in the brain to regulate thirst and salt-
appetite sensations. Angiotensin II drives both thirst and salt appetite; however, the neural …

[PDF][PDF] Mechanisms of fever production and lysis: lessons from experimental LPS fever

J Roth, CM Blatteis - Compr Physiol, 2014 - researchgate.net
Fever is a cardinal symptom of infectious or inflammatory insults, but it can also arise from
noninfectious causes. The fever-inducing agent that has been used most frequently in …