[HTML][HTML] Update on the diagnosis of tuberculosis

I Kontsevaya, AM Cabibbe, DM Cirillo… - Clinical Microbiology …, 2023 - Elsevier
Background Tuberculosis remains a global public health threat, and the development of
rapid and precise diagnostic tools is the key to enabling the early start of treatment …

Screening performance of C-reactive protein for active pulmonary tuberculosis in HIV-positive patients: A systematic review with a meta-analysis

AD Meca, A Turcu-Stiolica, M Bogdan… - Frontiers in …, 2022 - frontiersin.org
Background Tuberculosis (TB) is the leading infectious cause of mortality worldwide. In the
last years, resistant strains of the etiological agent, Mycobacterium tuberculosis, have …

Predicting the risk of active pulmonary tuberculosis in people living with HIV: development and validation of a nomogram

J Chen, L Li, T Chen, X Yang, H Ru, X Li, X Yang… - BMC infectious …, 2022 - Springer
Background Diagnosis of pulmonary tuberculosis (PTB) among people living with HIV
(PLHIV) was challenging. The study aimed to develop and validated a simple, convenient …

Derivation and external validation of a risk score for predicting HIV-associated tuberculosis to support case finding and preventive therapy scale-up: a cohort study

AF Auld, AD Kerkhoff, Y Hanifa, R Wood… - PLoS …, 2021 - journals.plos.org
Background Among people living with HIV (PLHIV), more flexible and sensitive tuberculosis
(TB) screening tools capable of detecting both symptomatic and subclinical active TB are …

Clinical predictors of pulmonary tuberculosis among South African adults with HIV

SC Mendelsohn, A Fiore-Gartland, D Awany… - …, 2022 - thelancet.com
Background Tuberculosis (TB) clinical prediction rules rely on presence of symptoms,
however many undiagnosed cases in the community are asymptomatic. This study aimed to …

Evaluating the efficacy of stool sample on Xpert MTB/RIF Ultra and its comparison with other sample types by meta-analysis for TB diagnostics

V Sharma, A Singh, M Gaur, D Rawat, A Yadav… - European Journal of …, 2022 - Springer
Precise and timely detection of tuberculosis (TB) is crucial to reduce transmission. This study
aims to assess the accuracy of Xpert MTB/RIF Ultra on stool samples and systematically …

Predictors contributing to the estimation of pulmonary tuberculosis among adults in a resource-limited setting: A systematic review of diagnostic predictions

GB Gebregergs, G Berhe, KG Gebrehiwot… - SAGE Open …, 2024 - journals.sagepub.com
Background: Although tuberculosis is highly prevalent in low-and middle-income countries,
millions of cases remain undetected using current diagnostic methods. To address this …

Development and validation of a risk prediction model for pulmonary tuberculosis among presumptive tuberculosis cases in Ethiopia

HF Wolde, ACA Clements, KA Alene - BMJ open, 2023 - bmjopen.bmj.com
Background Early diagnosis and treatment of tuberculosis (TB) is one of the key strategies to
achieve the WHO End TB targets. This study aimed to develop and validate a simple …

Host blood protein biomarkers to screen for Tuberculosis disease: a systematic review and meta-analysis

M Gaeddert, K Glaser, B Chendi, A Sultanli, L Koeppel… - medRxiv, 2024 - medrxiv.org
Introduction: Non-sputum tests are needed to improve TB diagnosis and close the diagnostic
gap. The World Health Organization target product profile (TPP) for point-of-care (POC) …

Clinical utility of WHO-recommended screening tools and development and validation of novel clinical prediction models for pulmonary tuberculosis screening among …

A Dhana, RK Gupta, Y Hamada… - European …, 2023 - Eur Respiratory Soc
Background: The World Health Organization (WHO) recommends that outpatient people
living with HIV (PLHIV) undergo tuberculosis screening with the WHO four-symptom screen …