Facioscapulohumeral muscular dystrophy (FSHD) is the third most common muscular
dystrophy after the dystrophinopathies and myotonic dystrophy and is associated with a …

Alternative splicing of pre-mRNAs is a major contributor to proteomic diversity and to the
control of gene expression in higher eukaryotic cells. For this reasons, alternative splicing is …

Facioscapulohumeral muscular dystrophy (FSHD), the most frequent muscular dystrophy, is
an autosomal dominant disease. In most individuals with FSHD, symptoms are restricted to …

Facioscapulohumeral dystrophy (FSHD) is a progressive muscular dystrophy caused by
decreased epigenetic repression of the D4Z4 macrosatellite repeats and ectopic expression …

The genetic lesion leading to facioscapulohumeral muscular dystrophy (FSHD) is a
dominant deletion at the 4q35 locus. The generally accepted disease model involves an …

Mutations in MECP2 (methyl-CpG-binding protein 2) are linked to the severe postnatal
neurodevelopmental disorder RTT (Rett syndrome). MeCP2 was originally characterized as …

ABSTRACT Facioscapulohumeral Muscular Dystrophy is a common form of muscular
dystrophy that presents clinically with progressive weakness of the facial, scapular, and …

Facioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to
contractions of the D4Z4 repeat array in 4q35. We have previously identified a double …

Treatment of dominantly inherited muscle disorders remains a difficult task considering the
need to eliminate the pathogenic gene product in a body-wide fashion. We show here that it …

Multiple molecular subtypes and distinct clinical outcomes in breast cancer, necessitate
specific therapy. Moreover, despite the improvements in breast cancer therapy, it remains …