Carrier screening allows individuals to learn their chance of passing on an autosomal or X-
linked condition to their offspring. Initially introduced as single-disease, ancestry-based …

Given the increasing research activity on epigenetics to monitor human diseases and its
connection with lifestyle and environmental expositions, the field of epigenetics has attracted …

Dynamic consent (DC) was originally developed in response to challenges to the informed
consent process presented by participants agreeing to 'future research'in biobanking. In the …

The incidence of cancer is continuing to rise and risk-tailored early diagnostic and/or primary
prevention strategies are urgently required. The ideal risk-predictive test should: integrate …

Empirical evidence suggests that while people hold the capacity to control their data in high
regard, they increasingly experience a loss of control over their data in the online world. The …

Over 100 million research participants around the world have had research array-based
genotyping (GT) or genome sequencing (GS), but only a small fraction of these have been …

To address the ethical challenges in big data health research we propose the concept of
systemic oversight. This approach is based on six defining features (adaptivity, flexibility …

Mobile health (mHealth) is rapidly being implemented and changing our ways of doing,
understanding and organising healthcare. mHealth includes wearable devices as well as …

Direct-to-consumer genetic testing (DTC-GT) has sparked much controversy and undergone
dramatic changes in its brief history. Debates over appropriate health policies regarding …

Abstract While Specific Informed Consent has been the established standard for obtaining
consent for medical research for many years, it does not appear suitable for large-scale …