Radiomics improves cancer screening and early detection
RJ Gillies, MB Schabath - Cancer Epidemiology, Biomarkers & Prevention, 2020 - AACR
Imaging is a key technology in the early detection of cancers, including X-ray
mammography, low-dose CT for lung cancer, or optical imaging for skin, esophageal, or …
mammography, low-dose CT for lung cancer, or optical imaging for skin, esophageal, or …
[HTML][HTML] Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer
KM Wadosky, S Koochekpour - Oncotarget, 2016 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most widely diagnosed male cancer in the Western World and
while low-and intermediate-risk PCa patients have a variety of treatment options, metastatic …
while low-and intermediate-risk PCa patients have a variety of treatment options, metastatic …
[HTML][HTML] Personalized medicine could transform healthcare
S Mathur, J Sutton - Biomedical reports, 2017 - spandidos-publications.com
Personalized medicine (PM) is about tailoring a treatment as individualized as the disease.
The approach relies on identifying genetic, epigenomic, and clinical information that allows …
The approach relies on identifying genetic, epigenomic, and clinical information that allows …
[HTML][HTML] Androgen receptor splice variants and prostate cancer: From bench to bedside
KM Wadosky, S Koochekpour - Oncotarget, 2017 - ncbi.nlm.nih.gov
Therapeutic interventions for advanced prostate cancer (PCa) center on inhibiting androgen
receptor (AR) and downstream signaling pathways. Resistance to androgen deprivation …
receptor (AR) and downstream signaling pathways. Resistance to androgen deprivation …
Plasma and urinary extracellular vesicles as a source of RNA biomarkers for prostate cancer in liquid biopsies
C Bajo-Santos, A Brokāne, P Zayakin… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: Extracellular vesicles (EVs) have emerged as a very attractive source of cancer-
derived RNA biomarkers for the early detection, prognosis and monitoring of various …
derived RNA biomarkers for the early detection, prognosis and monitoring of various …
Clinical relevance of circulating tumor cells in prostate cancer management
Given the low specificity of the routinely used biomarker prostate-specific antigen, circulating
tumor cell (CTC) enumeration seems to be particularly useful in the monitoring of prostate …
tumor cell (CTC) enumeration seems to be particularly useful in the monitoring of prostate …
Radical prostatectomy versus deferred treatment for localised prostate cancer
RWM Vernooij, M Lancee, A Cleves… - Cochrane Database …, 2020 - cochranelibrary.com
Background Prostate cancer is a common cancer but is oftentimes slow growing. When
confined to the prostate, radical prostatectomy (RP), which involves removal of the prostate …
confined to the prostate, radical prostatectomy (RP), which involves removal of the prostate …
[HTML][HTML] Correlation between apparent diffusion coefficient value on diffusion-weighted MR imaging and Gleason score in prostate cancer
X Wu, P Reinikainen, A Vanhanen, M Kapanen… - Diagnostic and …, 2017 - Elsevier
Objectives To investigate whether diffusion-weighted imaging (DWI) apparent diffusion
coefficient (ADC) correlates with prostate cancer aggressiveness and further to compare the …
coefficient (ADC) correlates with prostate cancer aggressiveness and further to compare the …
Precision intervention for prostate cancer: re-evaluating who is at risk
A Papachristodoulou, C Abate-Shen - Cancer letters, 2022 - Elsevier
The vast majority of new prostate cancer diagnoses are low-grade tumors that are monitored
by active surveillance rather than undergoing immediate treatment. However, a subset of …
by active surveillance rather than undergoing immediate treatment. However, a subset of …
Metabolomic profiling to evaluate the efficacy of proxalutamide, a novel androgen receptor antagonist, in prostate cancer cells
F Qu, Y Gu, Q Wang, M He, F Zhou, J Sun… - Investigational new …, 2020 - Springer
Proxalutamide is a newly developed androgen receptor (AR) antagonist for the treatment of
castration-resistant prostate cancer (PCa) that has entered phase III clinical trials. In the …
castration-resistant prostate cancer (PCa) that has entered phase III clinical trials. In the …