Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Background This is an overview of the mechanisms of obesity and its relation to
cardiovascular risks, describing the available treatment options to manage this condition …

The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

The SARS-CoV-2 pandemic continues to rage around the world. At the same time, despite
strong public health measures and high vaccination rates in some countries, a post-COVID …

Dipeptidyl peptidase-4 (DPP-4), also known as the T-cell antigen CD26, is a multi-functional
protein which, besides its catalytic activity, also functions as a binding protein and a ligand …

Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …

Aging and obesity induce ectopic adipocyte accumulation in bone marrow cavities. This
process is thought to impair osteogenic and hematopoietic regeneration. Here we specify …

Obesity increases the risk for metabolic, cardiovascular, chronic inflammatory, and several
malignant diseases and, therefore, may contribute to shortened lifespan. Adipokines are …

Abstract Dipeptidyl peptidase-4 (DPP4) is a widely expressed enzyme transducing actions
through an anchored transmembrane molecule and a soluble circulating protein. Both …