Highlights•Neuropeptide signaling forms a chemical connectome overlaid on synaptic
circuits.•Studies on nonbilaterians have revealed nonsynaptic actions of neuropeptides.• …

Cancer vaccine is regarded as an effective immunotherapy approach mediated by dendritic
cells (DCs) which are crucial for antigen presentation and the initiation of adaptive immune …

Peptides and proteins having D-amino acids in their sequences are now believed to be
widespread among different living organisms. Their significance is attributed to the diverse …

Peptide–receptor interactions play critical roles in a wide variety of physiological processes.
Methods to link bioactive peptides covalently to unmodified receptors on the surfaces of …

Understanding how natural and engineered peptides enter cells would facilitate the
elucidation of biochemical mechanisms underlying cell biology and is pivotal for developing …

Diversity, a hallmark of G protein-coupled receptor (GPCR) signaling, partly stems from
alternative splicing of a single gene generating more than one isoform for a receptor …

The function of endogenous cell-cell signaling peptides rely on their interactions with
cognate receptors, which in turn are influenced by the peptides' structures, necessitating a …

Allatotropin (AT) has been identified in many insects and plays important roles in the
regulation of their intestinal contraction, heart rate, ion transport, and digestive enzyme …

Knottins are very stable peptides (also called miniproteins) containing approximately 30
amino acid residues. Their structures are stabilized by three disulfide bonds forming a …