[HTML][HTML] Using source-associated mobile genetic elements to identify zoonotic extraintestinal E. coli infections

CM Liu, M Aziz, DE Park, Z Wu, M Stegger, M Li… - One Health, 2023 - Elsevier
A one-health perspective may provide new and actionable information about Escherichia
coli transmission. E. coli colonizes a broad range of vertebrates, including humans and food …

A national study confirms that Escherichia coli from Australian commercial layer hens remain susceptible to critically important antimicrobials

R Abraham, HS Allison, T Lee, A Pavic, R Chia… - Plos one, 2023 - journals.plos.org
Controlling the use of the most critically important antimicrobials (CIAs) in food animals has
been identified as one of the key measures required to curb the transmission of antimicrobial …

Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa

S Gervasoni, G Malloci, A Bosin, AV Vargiu… - Physical Chemistry …, 2022 - pubs.rsc.org
The drug/proton antiporter MexB is the engine of the major efflux pump MexAB-OprM in
Pseudomonas aeruginosa. This protein is known to transport a large variety of compounds …

Escherichia coli ST117: exploring the zoonotic hypothesis

ABS Saidenberg, SM Edslev, S Hallstrøm… - Microbiology …, 2024 - journals.asm.org
ABSTRACT Extraintestinal pathogenic Escherichia coli (ExPEC) can lead to severe
infections, with additional risks of increasing antimicrobial resistance rates. Genotypic …

In Vitro Demonstration of Targeted Phage Therapy and Competitive Exclusion as a Novel Strategy for Decolonization of Extended-Spectrum-Cephalosporin-Resistant …

T Laird, R Abraham, S Sahibzada… - Applied and …, 2022 - Am Soc Microbiol
Extended-spectrum cephalosporin-resistant (ESC-R) Escherichia coli have disseminated in
food-producing animals globally, attributed to horizontal transmission of bla CTX-M variants …

Genomic insights into anthropozoonotic tuberculosis in captive sun bears (Helarctos malayanus) and an Asiatic black bear (Ursus thibetanus) in Cambodia

K Officer, TM Walker, S Cheng, S Heng, M Hidé… - Scientific reports, 2024 - nature.com
Contact between humans and wildlife presents a risk for both zoonotic and
anthropozoonotic disease transmission. In this study we report the detection of human …

Machine learning and metagenomics reveal shared antimicrobial resistance profiles across multiple chicken farms and abattoirs in China

M Baker, X Zhang, A Maciel-Guerra, Y Dong, W Wang… - Nature Food, 2023 - nature.com
China is the largest global consumer of antimicrobials and improving surveillance methods
could help to reduce antimicrobial resistance (AMR) spread. Here we report the surveillance …

Augmented surveillance of antimicrobial resistance with high-throughput robotics detects transnational flow of fluoroquinolone-resistant Escherichia coli strain into …

A Truswell, ZZ Lee, M Stegger, J Blinco… - Journal of …, 2023 - academic.oup.com
Background Food animal AMR surveillance programs assess only small numbers of
Escherichia coli (from 100 to 600 per animal class) nationally each year, severely limiting …

Dissecting microbial communities and resistomes for interconnected humans, soil, and livestock

A Maciel-Guerra, M Baker, Y Hu, W Wang… - The ISME …, 2023 - academic.oup.com
A debate is currently ongoing as to whether intensive livestock farms may constitute
reservoirs of clinically relevant antimicrobial resistance (AMR), thus posing a threat to …

Development of an In Vivo Extended-Spectrum Cephalosporin-Resistant Escherichia coli Model in Post-Weaned Pigs and Its Use in Assessment of Dietary …

T Laird, D Jordan, J Pluske, J Mansfield, S Wilkinson… - Animals, 2023 - mdpi.com
Simple Summary Antimicrobial resistance in pork production has led to investigations and
analyses of alternate control strategies against bacterial infection. This study developed and …