Advancing the science of intervention scale-up is essential to increasing the impact of
effective interventions at the regional and national levels. In contrast with work in high …

Background The last decade has seen growing interest in scaling up of innovations to
strengthen healthcare systems. However, the lack of appropriate methods for determining …

Antimicrobial resistance (AMR) is a One Health problem underpinned by complex drivers
and behaviours. This is particularly so in low–and middle-income countries (LMICs), where …

Background: Achieving system-level, sustainable 'scale-up'of interventions is the epitome of
successful translation of evidence-based approaches in population health. In physical …

Policy Points More rigorous methodologies and systematic approaches should be
encouraged in the science of scaling. This will help researchers better determine the …

Over the last 4 decades, physical activity researchers have invested heavily in determining
“what works” to promote healthy behaviors in schools. Single and multicomponent school …

Introduction: Poor adoption of stroke guidelines is a problem internationally. The Quality in
Acute Stroke Care (QASC) trial demonstrated significant reduction in death and disability …

Community-based health promotion with a focus on people with social disadvantages is
essential to address persistently existing health inequities. However, achieving an impact on …

Background Human immunodeficiency virus (HIV) is the strongest known risk factor for
tuberculosis (TB) through its impairment of T-cell immunity. Tuberculosis preventive …

Background: Quality reporting contributes to effective translation of health research in
practice and policy. As an initial step in the development of a reporting guideline for scaling …