Is metabolic rate a universal 'pacemaker'for biological processes?
DS Glazier - Biological Reviews, 2015 - Wiley Online Library
ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …
Fundamental research questions in subterranean biology
Five decades ago, a landmark paper in Science titled The Cave Environment heralded
caves as ideal natural experimental laboratories in which to develop and address general …
caves as ideal natural experimental laboratories in which to develop and address general …
Scientists' warning on the conservation of subterranean ecosystems
In light of recent alarming trends in human population growth, climate change, and other
environmental modifications, a “Warning to humanity” manifesto was published in …
environmental modifications, a “Warning to humanity” manifesto was published in …
Alternative animal models of aging research
S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
Oxidative stress and hormesis in evolutionary ecology and physiology
D Costantini - A marriage between mechanistic and evolutionary …, 2014 - Springer
Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …
toxicological sciences have traditionally centralised such research, but in the last years we …
Oxidative damage, ageing, and life-history evolution: where now?
The idea that resources are limited and animals can maximise fitness by trading costly
activities off against one another forms the basis of life-history theory. Although investment in …
activities off against one another forms the basis of life-history theory. Although investment in …
Climate change going deep: The effects of global climatic alterations on cave ecosystems
Scientists of different disciplines have recognized the valuable role of terrestrial caves as
ideal natural laboratories in which to study multiple eco-evolutionary processes, from genes …
ideal natural laboratories in which to study multiple eco-evolutionary processes, from genes …
The African turquoise killifish: A research organism to study vertebrate aging and diapause
The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …
organism in the aging field. Our understanding of aging has strongly benefited from …
The free‐radical damage theory: accumulating evidence against a simple link of oxidative stress to ageing and lifespan
JR Speakman, C Selman - Bioessays, 2011 - Wiley Online Library
Recent work on a small European cave salamander (Proteus anguinus) has revealed that it
has exceptional longevity, yet it appears to have unexceptional defences against oxidative …
has exceptional longevity, yet it appears to have unexceptional defences against oxidative …
Neoteny, prolongation of youth: from naked mole rats to “naked apes”(humans)
VP Skulachev, S Holtze, MY Vyssokikh… - Physiological …, 2017 - journals.physiology.org
It has been suggested that highly social mammals, such as naked mole rats and humans,
are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot …
are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot …