Is metabolic rate a universal 'pacemaker'for biological processes?

DS Glazier - Biological Reviews, 2015 - Wiley Online Library
ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …

Fundamental research questions in subterranean biology

S Mammola, IR Amorim, ME Bichuette… - Biological …, 2020 - Wiley Online Library
Five decades ago, a landmark paper in Science titled The Cave Environment heralded
caves as ideal natural experimental laboratories in which to develop and address general …

Scientists' warning on the conservation of subterranean ecosystems

S Mammola, P Cardoso, DC Culver, L Deharveng… - …, 2019 - academic.oup.com
In light of recent alarming trends in human population growth, climate change, and other
environmental modifications, a “Warning to humanity” manifesto was published in …

Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Oxidative stress and hormesis in evolutionary ecology and physiology

D Costantini - A marriage between mechanistic and evolutionary …, 2014 - Springer
Research programmes on oxidative stress and hormesis are wide ranging. Biomedical and
toxicological sciences have traditionally centralised such research, but in the last years we …

Oxidative damage, ageing, and life-history evolution: where now?

C Selman, JD Blount, DH Nussey… - Trends in ecology & …, 2012 - cell.com
The idea that resources are limited and animals can maximise fitness by trading costly
activities off against one another forms the basis of life-history theory. Although investment in …

Climate change going deep: The effects of global climatic alterations on cave ecosystems

S Mammola, E Piano, P Cardoso… - The Anthropocene …, 2019 - journals.sagepub.com
Scientists of different disciplines have recognized the valuable role of terrestrial caves as
ideal natural laboratories in which to study multiple eco-evolutionary processes, from genes …

The African turquoise killifish: A research organism to study vertebrate aging and diapause

CK Hu, A Brunet - Aging cell, 2018 - Wiley Online Library
The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

The free‐radical damage theory: accumulating evidence against a simple link of oxidative stress to ageing and lifespan

JR Speakman, C Selman - Bioessays, 2011 - Wiley Online Library
Recent work on a small European cave salamander (Proteus anguinus) has revealed that it
has exceptional longevity, yet it appears to have unexceptional defences against oxidative …

Neoteny, prolongation of youth: from naked mole rats to “naked apes”(humans)

VP Skulachev, S Holtze, MY Vyssokikh… - Physiological …, 2017 - journals.physiology.org
It has been suggested that highly social mammals, such as naked mole rats and humans,
are long-lived due to neoteny (the prolongation of youth). In both species, aging cannot …