Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

PD Cani, C Depommier, M Derrien, A Everard… - Nature Reviews …, 2022 - nature.com
Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …

Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?

A Santoro, E Bientinesi, D Monti - Ageing research reviews, 2021 - Elsevier
During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Intestinal barrier in human health and disease

N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

Shaping the future of probiotics and prebiotics

M Cunningham, MA Azcarate-Peril, A Barnard… - Trends in …, 2021 - cell.com
Recent and ongoing developments in microbiome science are enabling new frontiers of
research for probiotics and prebiotics. Novel types, mechanisms, and applications currently …

Synergy and oxygen adaptation for development of next-generation probiotics

MT Khan, C Dwibedi, D Sundh, M Pradhan, JD Kraft… - Nature, 2023 - nature.com
The human gut microbiota has gained interest as an environmental factor that may
contribute to health or disease. The development of next-generation probiotics is a …

Roles of intestinal Parabacteroides in human health and diseases

Y Cui, L Zhang, X Wang, Y Yi, Y Shan… - FEMS microbiology …, 2022 - academic.oup.com
The stability of gut microbiota is essential for the host's health. Parabacteroides spp., core
members of the human gut microbiota, have an average abundance of 1.27% in humans of …

Microbiome definition re-visited: old concepts and new challenges

G Berg, D Rybakova, D Fischer, T Cernava… - Microbiome, 2020 - Springer
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in …

Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health

WJY Chee, SY Chew, LTL Than - Microbial cell factories, 2020 - Springer
Human vagina is colonised by a diverse array of microorganisms that make up the normal
microbiota and mycobiota. Lactobacillus is the most frequently isolated microorganism from …

Postbiotics-parabiotics: The new horizons in microbial biotherapy and functional foods

BH Nataraj, SA Ali, PV Behare, H Yadav - Microbial cell factories, 2020 - Springer
Probiotics have several health benefits by modulating gut microbiome; however, techno-
functional limitations such as viability controls have hampered their full potential applications …