[图书][B] Melatoninergic system in the skin

AT Slominski, MA Zmijewski, C Skobowiat, B Zbytek… - 2012 - Springer
Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …

Neuroendocrine pharmacology of stress

GA Carrasco, LD Van de Kar - European journal of pharmacology, 2003 - Elsevier
Exposure to hostile conditions initiates responses organized to enhance the probability of
survival. These coordinated responses, known as stress responses, are composed of …

Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABAA receptor subunits in frontal cortical brain region

Z Merali, L Du, P Hrdina, M Palkovits… - Journal of …, 2004 - Soc Neuroscience
Corticotropin-releasing hormone (CRH) and GABA have been implicated in depression, and
there is reason to believe that GABA may influence CRH functioning. The levels of CRH, and …

The CRF peptide family and their receptors: yet more partners discovered

FM Dautzenberg, RL Hauger - Trends in pharmacological sciences, 2002 - cell.com
Abnormal signaling at corticotropin-releasing factor CRF 1 and CRF 2 receptors might
contribute to the pathophysiology of stress-related disorders such as anxiety, depression …

Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets

RL Hauger, V Risbrough, O Brauns… - CNS & Neurological …, 2006 - ingentaconnect.com
Corticotropin-releasing factor (CRF) and the related urocortin peptides mediate behavioral,
cognitive, autonomic, neuroendocrine and immunologic responses to aversive stimuli by …

The pathogenesis of clinical depression: stressor-and cytokine-induced alterations of neuroplasticity

S Hayley, MO Poulter, Z Merali, H Anisman - Neuroscience, 2005 - Elsevier
Stressful events promote neurochemical changes that may be involved in the provocation of
depressive disorder. In addition to neuroendocrine substrates (eg corticotropin releasing …

Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders

H Anisman, Z Merali, S Hayley - Progress in neurobiology, 2008 - Elsevier
Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …

Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders

A Holmes, M Heilig, NMJ Rupniak, T Steckler… - Trends in …, 2003 - cell.com
The health burden of stress-related diseases, including depression and anxiety disorders, is
rapidly increasing, whereas the range of available pharmacotherapies to treat these …

Persistent neuroendocrine and behavioral effects of a novel, etiologically relevant mouse paradigm for chronic social stress during adolescence

MV Schmidt, V Sterlemann, K Ganea, C Liebl… - …, 2007 - Elsevier
Chronic stress is widely regarded as a key risk factor for a variety of diseases. A large
number of paradigms have been used to induce chronic stress in rodents. However, many of …

[图书][B] Rethinking homeostasis: Allostatic regulation in physiology and pathophysiology

J Schulkin - 2003 - books.google.com
An overview of allostasis, the process by which the body maintains overall viability under
normal and adverse conditions. Homeostasis, a key concept in biology, refers to the …