The analysis of polymorphism data is becoming increasingly important as a complementary
tool to classical genetic analyses. Nevertheless, despite plunging sequencing costs …

Evolve and resequence (E&R) is a new approach to investigate the genomic responses to
selection during experimental evolution. By using whole genome sequencing of pools of …

The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …

Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

In the 1950s the myxoma virus was released into European rabbit populations in Australia
and Europe, decimating populations and resulting in the rapid evolution of resistance. We …

Flies of the genus Drosophila, and particularly those of the species Drosophila
melanogaster, are best known as laboratory organisms. As with all model organisms, they …

Immune cells provide defense against non‐self and have recently been shown to also play
key roles in diverse processes such as development, metabolism, and tumor progression …

Understanding the genetic architecture (causal molecular variants, their effects, and
frequencies) of quantitative traits is important for precision agriculture and medicine and …

Wolbachia is a maternally transmitted bacterium that lives inside arthropod cells. Historically,
it was viewed primarily as a parasite that manipulates host reproduction, but more recently it …

The fruit fly Drosophila melanogaster has been a valuable model to investigate the genetic
mechanisms of innate immunity. Initially focused on the resistance to bacteria and fungi …