Diagnosis and treatment of primary aldosteronism
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …
Aldosterone as a mediator of cardiovascular damage
Besides the physiological regulation of water, sodium, and potassium homeostasis,
aldosterone modulates several physiological and pathological processes in the …
aldosterone modulates several physiological and pathological processes in the …
Primary aldosteronism—a multidimensional syndrome
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
Primary aldosteronism: state-of-the-art review
A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
Evolution of the primary aldosteronism syndrome: updating the approach
Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …
Aldosterone in chronic kidney disease and renal outcomes
Aims Randomized controlled trials have demonstrated the efficacy of mineralocorticoid
receptor (MR) antagonism in delaying chronic kidney disease (CKD) progression in …
receptor (MR) antagonism in delaying chronic kidney disease (CKD) progression in …
Subclinical primary aldosteronism and cardiovascular health: a population-based cohort study
BACKGROUND: Primary aldosteronism, characterized by overt renin-independent
aldosterone production, is a common but underrecognized form of hypertension and …
aldosterone production, is a common but underrecognized form of hypertension and …
Oxidative stress in arterial hypertension (HTN): The nuclear factor erythroid factor 2-related factor 2 (Nrf2) pathway, implications and future perspectives
Arterial hypertension (HTN) is one of the most prevalent entities globally, characterized by
increased incidence and heterogeneous pathophysiology. Among possible etiologies …
increased incidence and heterogeneous pathophysiology. Among possible etiologies …
Cardiac structure and function across the spectrum of aldosteronism: the atherosclerosis risk in communities study
JM Brown, MO Wijkman, BL Claggett, AM Shah… - …, 2022 - Am Heart Assoc
Background: Aldosterone production and mineralocorticoid receptor activation are
implicated in myocardial fibrosis and cardiovascular events. Methods: Cardiac structure and …
implicated in myocardial fibrosis and cardiovascular events. Methods: Cardiac structure and …
Urinary stress hormones, hypertension, and cardiovascular events: the multi-ethnic study of atherosclerosis
K Inoue, T Horwich, R Bhatnagar, K Bhatt… - …, 2021 - Am Heart Assoc
Psychosocial stress is a key contributing factor to the pathogenesis of hypertension and
cardiovascular disease. We examined the association of urinary stress hormone levels with …
cardiovascular disease. We examined the association of urinary stress hormone levels with …