S100B as a marker for brain damage and blood–brain barrier disruption following exercise

SXT Koh, JKW Lee - Sports Medicine, 2014 - Springer
Background S100B level in the blood has been used as a marker for brain damage and
blood–brain barrier (BBB) disruption. Elevations of S100B levels after exercise have been …

Current status of fluid biomarkers in mild traumatic brain injury

JR Kulbe, JW Geddes - Experimental neurology, 2016 - Elsevier
Mild traumatic brain injury (mTBI) affects millions of people annually and is difficult to
diagnose. Mild injury is insensitive to conventional imaging techniques and diagnoses are …

Update on protein biomarkers in traumatic brain injury with emphasis on clinical use in adults and pediatrics

E Kövesdi, J Lückl, P Bukovics, O Farkas, J Pál… - Acta …, 2010 - Springer
Purpose This review summarizes protein biomarkers in mild and severe traumatic brain
injury in adults and children and presents a strategy for conducting rationally designed …

A novel, ultrasensitive assay for tau: potential for assessing traumatic brain injury in tissues and biofluids

R Rubenstein, B Chang, P Davies… - Journal of …, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a cause of death and disability and can lead to tauopathy-
related dementia at an early age. Pathologically, TBI results in axonal injury that is coupled …

Cleaved-tau: a biomarker of neuronal damage after traumatic brain injury

SP Gabbita, SW Scheff, RM Menard… - Journal of …, 2005 - liebertpub.com
Previous studies from our laboratory indicate that traumatic brain injury (TBI) in humans
results in proteolysis of neuronally-localized, intracellular microtubule associated protein …

Nonspecific increase of systemic neuron-specific enolase after trauma: clinical and experimental findings

LE Pelinka, H Hertz, W Mauritz, N Harada… - Shock, 2005 - journals.lww.com
The aim of this clinical and experimental study was to determine whether systemic neuron-
specific enolase (NSE) is a useful early marker of traumatic brain injury (TBI) and whether …

Repeated mild injury causes cumulative damage to hippocampal cells

JE Slemmer, EJT Matser, CI De Zeeuw, JT Weber - Brain, 2002 - academic.oup.com
An interesting hypothesis in the study of neurotrauma is that repeated traumatic brain injury
may result in cumulative damage to cells of the brain. However, post‐injury sequelae are …

S-100β and neuron-specific enolase levels in carbon monoxide–related brain injury

Z Cakir, S Aslan, Z Umudum, H Acemoglu… - The American journal of …, 2010 - Elsevier
INTRODUCTION: Carbon monoxide (CO) toxicity may cause persistent injuries in tissues
sensitive to hypoxia. Neuropsychiatric sequelae may be observed in about 67% of cases …

Relationship between injury severity and serum tau protein levels in traumatic brain injured rats

PC Liliang, CL Liang, K Lu, KW Wang, HC Weng… - Resuscitation, 2010 - Elsevier
BACKGROUND: Although serum tau protein levels increase following TBI, the time course is
unknown. The aim of the present study was to determine whether serum tau protein levels …

[PDF][PDF] Serum biomarkers for traumatic brain injury

MD Neher, CN Keene, MC Rich, HB Moore, PF Stahel - South Med J, 2014 - academia.edu
There is a lack of reliable serum biomarkers for routine use in the diagnostic workup of
people with traumatic brain injury. Multiple biomediators and biomarkers have been …