Genetic factors can, to a certain extent, successfully predict the therapeutic effects,
metabolism, and adverse reactions of drugs. This research field, pharmacogenomics, is well …

Considerable efforts have been exerted to implement Pharmacogenomics (PGx), the study
of interindividual variations in DNA sequence related to drug response, into routine clinical …

Abstract The Dutch Pharmacogenetics Working Group (DPWG) guideline presented here,
presents the gene-drug interaction between the genes CYP2C19 and CYP2D6 and …

In psychiatry, the selection of antipsychotics and antidepressants is generally led by a trial-
and-error approach. The prescribing of these medications is complicated by sub-optimal …

Summary Background Pharmacogenomics (PGx) holds promise to revolutionize modern
healthcare. Although there are several prospective clinical studies in oncology and …

Polymorphisms of genes encoding drug metabolizing enzymes and transporters can
significantly modify pharmacokinetics, and this can be associated with significant differences …

The major challenges that delay the implementation of pharmacogenomics based clinical
practice in the developing countries, primarily the low-and middle-income countries need to …

Pharmacogenetic (PGx) testing has emerged as a tool for predicting a person's ability to
process and react to drugs. Despite the growing evidence‐base, enthusiasm, and …

Aim To determine the efficacy and safety of pharmacogenomics (PGx)-guided
antidepressant prescribing in patients with depression through an umbrella review and …

The study aimed to conduct a meta-analysis of studies comparing pharmacogenetically
guided dosing of antidepressants with empiric standard of care. Publications referring to …