CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …

Research on matrix metalloproteinases (MMPs) and in particular on gelatinase B, alias MMP-
9, has grown exponentially in the decade 2003–2012. Structural details about flexibility of …

Reconstruction of massive bone defects is challenging for orthopaedic clinicians, especially
in cases of severe trauma and resection of tumors in various locales. Autologous iliac crest …

Matrix metalloproteinases (MMPs) are the major protease family responsible for the
cleavage of the matrisome (global composition of the extracellular matrix (ECM) proteome) …

CD44 is a major cell surface receptor for the glycosaminoglycan hyaluronan (HA). Native
high molecular weight hyaluronan (nHA) and oligosaccharides of hyaluronan (oHA) provoke …

The matrix metalloproteinases (MMP)-2 and-9, also known as the gelatinases have been
long recognized as major contributors to the proteolytic degradation of extracellular matrix …

The regeneration of adult skeletal tissues requires the timely recruitment of skeletal
progenitor cells to an injury site, the differentiation of these cells into bone or cartilage, and …

During carcinoma progression, tumor cells often undergo changes similar (but not identical)
to epithelialmesenchymal transitions in embryonic development. In this study, we …

Osteoclast differentiation is tightly regulated by receptor activator of NF-κB ligand (RANKL)
signaling. Matrix metalloproteinase-9 (MMP-9), a type IV collagenase is highly expressed in …

The current challenge in treating periodontitis is regenerating the periodontium. This
motivates tissue‐engineering researchers to develop scaffolds as artificial matrices that give …