The brain is a vital organ, susceptible to alterations under genetic influences and
environmental experiences. Social isolation (SI) acts as a stressor which results in …

Major depressive disorder (MDD) is a life‐threatening disease that presents several
characteristics. The pathogenesis of depression still remains poorly understood. Moreover …

Mother-infant contact has a critical role on brain development and behavior. Experiencing
early-life adversities (such as maternal separation stress or MS in rodents) results in …

Depression and anxiety are common comorbid disorders observed in patients with
inflammatory bowel disease (IBD). Increasing line of evidence indicates that immune …

Mitochondria are cellular organelles essential for energy metabolism and antioxidant
defense. Mitochondrial impairment is implicated in many psychiatric disorders, including …

In the past couple of decades, major efforts were made to increase reliability of metabolic
assessments by magnetic resonance methods. Magnetic resonance spectroscopy (MRS) …

Social behavior is essential for the well-being and survival of individuals. However, social
isolation is a serious public health issue, especially during the COVID-19 pandemic …

Depression is one of the main factors affecting our daily performance. Among many putative
compounds with effect on behavioral and pathophysiological alterations in depression …

Many neuropsychiatric disorders show localized dysfunction in specific cortical regions. The
mechanisms underlying such region-specific vulnerabilities are unknown. Post-mortem …

This review describes the role of social isolation in the development of anxiety and
depression-like behavior in rodents. The duration of social isolation, age from onset of social …