In the last few decades, multiscale modelling has emerged as one of the dominant
modelling paradigms in many areas of science and engineering. Its rise to dominance is …

Abstract System-of-systems approaches for integrated assessments have become prevalent
in recent years. Such approaches integrate a variety of models from different disciplines and …

Following a review of multiscale simulation methodology, and previous examples of
multiscale models from food science, we present our multiscale simulation framework MULTI …

The inherent complexity of biomedical systems is well recognized; they are multiscale,
multiscience systems, bridging a wide range of temporal and spatial scales. While the …

Planning support for industrial production systems aims at reducing production-related costs
and environmental impacts while creating required products with a desired quality …

Inherently complex problems from many scientific disciplines require a multiscale modeling
approach. Yet its practical contents remain unclear and inconsistent. Moreover, multiscale …

Neointimal hyperplasia, a process of smooth muscle cell re-growth, is the result of a natural
wound healing response of the injured artery after stent deployment. Excessive neointimal …

In-stent restenosis, the maladaptive response of a blood vessel to injury caused by the
deployment of a stent, is a multiscale system involving a large number of biological and …

Multiscale modelling and simulation typically entails coupling multiple simulation codes into
a single program. Doing this in an ad-hoc fashion tends to result in a tightly coupled, difficult …

In this paper, we report on the experimental results of running a large, tightly coupled,
distributed multiscale computation over a hybrid High Performance Computing (HPC) …