Malignant mesothelioma is an aggressive, treatment-resistant tumour, which is increasing in
frequency throughout the world. Although the main risk factor is asbestos exposure, a virus …

Several chronic infections known to be associated with malignancy have established
oncogenic properties. However the existence of chronic inflammatory conditions that do not …

Molecular studies suggest that the simian polyomavirus SV40 is present in the human
population, possibly introduced in contaminated polio vaccine. However, no recent …

Malignant pleural mesothelioma (MPM) is a deadly disease that occurs in 2,000 to 3,000
people each year in the United States. Although MPM is an extremely difficult disease to …

Abstract Simian virus 40 (SV40), a polyomavirus of rhesus macaque origin, was discovered
in 1960 as a contaminant of polio vaccines that were distributed to millions of people from …

Viruses are the causative agents of 10%–15% of human cancers worldwide. The most
common outcome for virus-induced reprogramming is genomic instability, including …

In spite of the well-recognized health hazards of asbestos and the imposition, beginning in
1971, of increasingly strict exposure limits, the prevalence of patients with pleural …

JC virus (JCV) is a polyoma virus that commonly infects humans. We have found T antigen
DNA sequences of JCV in the mucosa of normal human colons, colorectal cancers …

Recent studies have demonstrated that angiogenesis and suppressed cell-mediated
immunity (CMI) play a central role in the pathogenesis of malignant disease facilitating …

Mesothelioma, a malignancy associated with asbestos, has been recently linked to simian
virus 40 (SV40). We found that infection of human mesothelial cells by SV40 is very different …