(E)-2-((3-nitrophenyl) diazenyl)-3-oxo-3-phenylpropanal: experimental, DFT studies, and molecular docking investigations
EC Agwamba, H Louis, I Benjamin, CG Apebende… - Chemistry Africa, 2022 - Springer
In 2019 alone, the WHO declared about 325 million people worldwide to be infected with
hepatitis, resulting to mortality of about 1.4 million annually. In this study the potential of (E)-2 …
hepatitis, resulting to mortality of about 1.4 million annually. In this study the potential of (E)-2 …
Recent advances in influenza, HIV and SARS-CoV-2 infection prevention and drug treatment—the need for precision medicine
T Kálai, JE Pongrácz, P Mátyus - Chemistry, 2022 - mdpi.com
Viruses, and in particular, RNA viruses, dominate the WHO's current list of ten global health
threats. Of these, we review the widespread and most common HIV, influenza virus, and …
threats. Of these, we review the widespread and most common HIV, influenza virus, and …
Structure-based design and synthesis of copper (II) complexes as antivirus drug candidates targeting SARS CoV-2 and HIV
S Kumar, M Choudhary - New Journal of Chemistry, 2022 - pubs.rsc.org
This paper describes the structure-based design and synthesis of two novel square-planar
trans-N2O2 Cu (II) complexes [Cu (L1) 2](1) and [Cu (L2) 2](2) of 2-((Z)-(4 …
trans-N2O2 Cu (II) complexes [Cu (L1) 2](1) and [Cu (L2) 2](2) of 2-((Z)-(4 …
Comparative molecular docking and toxicity between carbon-capped metal oxide nanoparticles and standard drugs in cancer and bacterial infections
Introduction: Nanoparticles (NPs) are of great interest in the design of various drugs due to
their high surface-to-volume ratio, which result from their unique physicochemical properties …
their high surface-to-volume ratio, which result from their unique physicochemical properties …
[PDF][PDF] In silico targeting CYP51 of Naegleria fowleri using bioactive compounds from Indonesian plants
N Daniel, F Ferdinand… - Journal of Pharmacy & …, 2023 - pdfs.semanticscholar.org
Context: Given the elusive nature of Primary Amoebic Meningoencephalitis (PAM), caused
by Naegleria fowleri, early detection is vital, yet challenging due to limited clinical indicators …
by Naegleria fowleri, early detection is vital, yet challenging due to limited clinical indicators …
Evaluating Terrestrol A as an Inhibitor Against SARS‐CoV‐2and Invasive Fungal Pathogens: A Comprehensive Computational Analysis
B Singha, B Arora, R Karmaker, K Richa… - …, 2024 - Wiley Online Library
The highly contagious SARS‐CoV‐2 virus, which initiated the COVID‐19 pandemic, has
resulted in a significant loss of life worldwide. While vaccines and therapeutics have helped …
resulted in a significant loss of life worldwide. While vaccines and therapeutics have helped …
Multi-target activity of copper complexes: Antibacterial, DNA binding, and molecular docking with SARS-CoV-2 receptor
A series of pendant-armed mixed-ligand copper (II) complexes of the type [CuL 1-3
(diimine)](1–6) have been synthesized by the reaction of pendant-armed ligands N, N-bis (2 …
(diimine)](1–6) have been synthesized by the reaction of pendant-armed ligands N, N-bis (2 …
In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds
Abstract Hepatitis E Virus (HEV) follows waterborne or zoonotic/foodborne transmission.
Genotype 3 HEV infections are worldwide spread, especially in swine populations …
Genotype 3 HEV infections are worldwide spread, especially in swine populations …
Inhibition of human epidermal growth factor receptor-2 protein by some alkaloid inhibitors
Abstract Background Human Epidermal Growth Factor Receptor-2 (HER2), a
transmembrane tyrosine kinase receptor, has been associated with several types of cancer …
transmembrane tyrosine kinase receptor, has been associated with several types of cancer …
Synergistic effects of steric constraints and non-covalent interactions in copper (ii) chloro-nitro-benzoato complexes: synthesis, structural characterization, theoretical …
Herein, the design and synthesis of three new copper (II) chloro-benzoato complexes
(2C4NB= 2-chloro-4-nitrobenzoate; 2C5NB= 2-chloro-5-nitrobenzoate) with N-/O-donor, ie …
(2C4NB= 2-chloro-4-nitrobenzoate; 2C5NB= 2-chloro-5-nitrobenzoate) with N-/O-donor, ie …