Halfway through the twentieth century, fluoride piqued the interest of toxicologists due to its
deleterious effects at high concentrations in human populations suffering from fluorosis and …

Fluorides are present in the environment. Excessive systemic exposure to fluorides can lead
to disturbances of bone homeostasis (skeletal fluorosis) and enamel development …

Sulfur (VI) Fluoride Exchange (SuFEx) is a new family of click chemistry transformations
which relies on readily available materials to produce compounds bearing the SVI–F motif …

Fluoride is an effective caries prophylactic, but at high doses can also be an environmental
health hazard. Acute or chronic exposure to high fluoride doses can result in dental enamel …

Fluoride (F) is a naturally occurring contaminant in the water. F is essential for normal
maintenance of teeth and bones. However, prolonged exposure to high concentration of F is …

Fluoride (F) is ubiquitous natural substance and widespread industrial pollutant. Although
low fluoride concentrations are beneficial for normal tooth and bone development, acute or …

The mechanism of how fluoride causes fluorosis remains unknown. Exposure to fluoride can
inhibit protein synthesis, and this may also occur by agents that cause endoplasmic …

Objective To investigate the effects of fluoride on lipid peroxidation, DNA damage and
apoptosis in human embryo hepatocyte L-02 cells. Methods Lipid peroxide (LPO) level …

AIM: To study the effect of fluoride on oxidative stress, DNA damage and apoptosis as well
as cell cycle of rat oral mucosal cells and hepatocytes. METHODS: Ten male SD rats …

Mitochondrial reactive oxygen species (ROS) production has been implicated in the
pathogenesis of fluoride toxicity in liver. Melatonin, an indolamine synthesized in the pineal …