Fluid dynamics inside the brain barrier: current concept of interstitial flow, glymphatic flow, and cerebrospinal fluid circulation in the brain
T Nakada, IL Kwee - The Neuroscientist, 2019 - journals.sagepub.com
The discovery of the water specific channel, aquaporin, and abundant expression of its
isoform, aquaporin-4 (AQP-4), on astrocyte endfeet brought about significant advancements …
isoform, aquaporin-4 (AQP-4), on astrocyte endfeet brought about significant advancements …
Fluid metabolic pathways after subarachnoid hemorrhage
J Zhou, P Guo, Z Guo, X Sun, Y Chen… - Journal of …, 2022 - Wiley Online Library
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating cerebrovascular disease
with high mortality and morbidity. In recent years, a large number of studies have focused on …
with high mortality and morbidity. In recent years, a large number of studies have focused on …
[HTML][HTML] Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood–brain barrier:[: 17: O] H: 2: O JJVCPE MRI study
VJ Huber, H Igarashi, S Ueki, IL Kwee, T Nakada - Neuroreport, 2018 - journals.lww.com
The blood–brain barrier (BBB), which imposes significant water permeability restriction,
effectively isolates the brain from the systemic circulation. Seemingly paradoxical, the …
effectively isolates the brain from the systemic circulation. Seemingly paradoxical, the …
Brain glymphatic/lymphatic imaging by MRI and PET
DS Lee, M Suh, A Sarker, Y Choi - Nuclear Medicine and Molecular …, 2020 - Springer
Since glymphatic was proposed and meningeal lymphatic was discovered, MRI and even
PET were introduced to investigate brain parenchymal interstitial fluid (ISF), cerebrospinal …
PET were introduced to investigate brain parenchymal interstitial fluid (ISF), cerebrospinal …
[HTML][HTML] Erythropoietin-mediated activation of aquaporin-4 channel for the treatment of experimental hydrocephalus
M Rizwan Siddiqui, F Attar, V Mohanty, KS Kim… - Child's Nervous …, 2018 - Springer
Objective In this study, we investigate a neuroprotective agent, erythropoietin (EPO), in
animal hydrocephalus model and its potential reversal effects on hydrocephalus by altering …
animal hydrocephalus model and its potential reversal effects on hydrocephalus by altering …
[HTML][HTML] Application of 7 tesla magnetic resonance imaging for pediatric neurological disorders: early clinical experience
K Yamada, J Yoshimura, M Watanabe… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Ultra-high field magnetic resonance imaging (MRI) has been introduced for use in pediatric
developmental neurology. While higher magnetic fields have certain advantages, optimized …
developmental neurology. While higher magnetic fields have certain advantages, optimized …
Light and the Brain: A Clinical Case Depicting the Effects of Light on Brainwaves and Possible Presence of Plasma-like Brain Energy
Light is an electromagnetic radiation that has visible and invisible wavelength spectrums.
Visible light can only be detected by the eyes through the optic pathways. With the presence …
Visible light can only be detected by the eyes through the optic pathways. With the presence …
[HTML][HTML] Reduced pituitary volume with relative T1 shortening correlates with behavior in Prader-Willi syndrome
K Yamada, M Watanabe, K Suzuki - Biomarkers in Neuropsychiatry, 2021 - Elsevier
Prader-Willi syndrome is a complex endocrinological and developmental disorder
characterized by hyperphagic, autistic, and obsessive behaviors, which have been …
characterized by hyperphagic, autistic, and obsessive behaviors, which have been …
Hydrocephalus shunt therapy: current titanium shunt valve implants obstructed by internal tissue proliferations identified as extracellular matrix membranes
HC Ludwig, M Reitemeyer, HC Bock, M Sigler - Child's Nervous System, 2020 - Springer
Purpose Shunt valves, required for treatment of hydrocephalus, demand for high
performance rates and lifelong excellent function. To overcome problems with traditional …
performance rates and lifelong excellent function. To overcome problems with traditional …
The Brain in Prader-Willi Syndrome
K Yamada - Eating Disorders, 2023 - Springer
Abstract Prader-Willi syndrome (PWS), a congenital genetic disorder, has received attention
due to its features, including hyperphagic behavior with a unique genetic background. While …
due to its features, including hyperphagic behavior with a unique genetic background. While …