Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Metal organic frameworks based on bioactive components

S Rojas, T Devic, P Horcajada - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
One of the more recent and promising domains of the application of Metal Organic
Frameworks (MOFs) is the biomedical one. To fulfil the keystone requirements of …

[HTML][HTML] A novel sprayable thermosensitive hydrogel coupled with zinc modified metformin promotes the healing of skin wound

Z Liu, W Tang, J Liu, Y Han, Q Yan, Y Dong, X Liu… - Bioactive Materials, 2023 - Elsevier
A novel sprayable adhesive is established (ZnMet-PF127) by the combination of a
thermosensitive hydrogel (Pluronic F127, PF127) and a coordination complex of zinc and …

Biguanide iridium (III) complexes with potent antimicrobial activity

F Chen, J Moat, D McFeely, G Clarkson… - Journal of Medicinal …, 2018 - ACS Publications
We have synthesized novel organoiridium (III) antimicrobial complexes containing a
chelated biguanide, including the antidiabetic drug metformin. These 16-and 18-electron …

Biguanides: Species with versatile therapeutic applications

D Kathuria, AD Raul, P Wanjari, PV Bharatam - European Journal of …, 2021 - Elsevier
Biguanides are compounds in which two guanidine moieties are fused to form a highly
conjugated system. Biguanides are highly basic and hence they are available as salts …

Copper nanoparticles encapsulated in reduced graphene oxide electrode (CuxrGO1-x) for the electrochemical quantification of metformin in water

YJ Shih, YQ Su, WH Chen, SK Lin, YC He… - Chemical Engineering …, 2023 - Elsevier
Electrochemical oxidation of anti-diabetic metformin (MTF) drug was studied on glassy
carbon electrode (GCE) prepared by electroplating of copper nanoparticles (Cu NPs) on …

[HTML][HTML] Design, synthesis and in vivo evaluation of 3-arylcoumarin derivatives of rhenium (I) tricarbonyl complexes as potent antibacterial agents against methicillin …

SN Sovari, S Vojnovic, SS Bogojevic, A Crochet… - European journal of …, 2020 - Elsevier
We have prepared a series of ten 3-arylcoumarin molecules, their respective fac-[Re (CO) 3
(bpy) L]+ and fac-[Re (CO) 3 (L⁀ L) Br] complexes and tested all compounds for their …

[HTML][HTML] Metal complexes—a promising approach to target biofilm associated infections

R Olar, M Badea, MC Chifiriuc - Molecules, 2022 - mdpi.com
Microbial biofilms are represented by sessile microbial communities with modified gene
expression and phenotype, adhered to a surface and embedded in a matrix of self-produced …

[HTML][HTML] Biological properties of transition metal complexes with metformin and its analogues

DA Rusanov, J Zou, MV Babak - Pharmaceuticals, 2022 - mdpi.com
Metformin is a widely prescribed medication for the treatment and management of type 2
diabetes. It belongs to a class of biguanides, which are characterized by a wide range of …

[HTML][HTML] Synthesis and in-silico simulation of some new bis-thiazole derivatives and their preliminary antimicrobial profile: investigation of hydrazonoyl chloride …

RM Kassab, SM Gomha, SA Al-Hussain… - Arabian Journal of …, 2021 - Elsevier
Two new series of bis-thiazoles 6a-f and bis-thiazolones 9a-d were prepared via reacting bis-
thiosemicarbazone 3 with hydrazonoyl chloride derivatives 4a-f and 7a-d, respectively, in …