Marine natural products

JW Blunt, BR Copp, MHG Munro, PT Northcote… - Natural product …, 2004 - pubs.rsc.org
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …

Bioactive sesterterpenes and triterpenes from marine sponges: Occurrence and pharmacological significance

SS Ebada, WH Lin, P Proksch - Marine Drugs, 2010 - mdpi.com
Marine ecosystems (> 70% of the planet's surface) comprise a continuous resource of
immeasurable biological activities and immense chemical entities. This diversity has …

Natural products reveal cancer cell dependence on oxysterol-binding proteins

AWG Burgett, TB Poulsen, K Wangkanont… - Nature chemical …, 2011 - nature.com
Abstract Cephalostatin 1, OSW-1, ritterazine B and schweinfurthin A are natural products
that potently, and in some cases selectively, inhibit the growth of cultured human cancer cell …

Target identification of natural and traditional medicines with quantitative chemical proteomics approaches

J Wang, L Gao, YM Lee, KA Kalesh, YS Ong… - Pharmacology & …, 2016 - Elsevier
Natural and traditional medicines, being a great source of drugs and drug leads, have
regained wide interests due to the limited success of high-throughput screening of …

Application of diffusion growth chambers for the cultivation of marine sponge-associated bacteria

G Steinert, S Whitfield, MW Taylor, C Thoms… - Marine …, 2014 - Springer
Marine sponges contain dense and diverse microbial communities, which are renowned as
a source of bioactive metabolites. The biological activities of sponge-microbe natural …

[HTML][HTML] Marine compounds targeting the PI3K/Akt signaling pathway in cancer therapy

J Wei, Z Gou, Y Wen, Q Luo, Z Huang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Cancer is a disease characterized by overproliferation, including that due to transformation,
apoptosis disorders, proliferation, invasion, angiogenesis and metastasis, and is one of the …

Triterpenoids of marine origin as anti-cancer agents

YX Li, SWA Himaya, SK Kim - Molecules, 2013 - mdpi.com
Triterpenoids are the most abundant secondary metabolites present in marine organisms,
such as marine sponges, sea cucumbers, marine algae and marine-derived fungi. A large …

Stellettin B induces cell death in bladder cancer via activating the autophagy/DAPK2/apoptosis signaling cascade

CH Chang, BJ Lin, CH Chen, NL Nguyen, TH Hsieh… - Marine Drugs, 2023 - mdpi.com
Bladder cancer (BC) is one of the most prevalent cancers worldwide. However, the
recurrence rate and five-year survival rate have not been significantly improved in advanced …

Molecular Phylogeny of the Astrophorida (Porifera, Demospongiaep) Reveals an Unexpected High Level of Spicule Homoplasy

P Cárdenas, JR Xavier, J Reveillaud, C Schander… - PLoS …, 2011 - journals.plos.org
Background The Astrophorida (Porifera, Demospongiae p) is geographically and
bathymetrically widely distributed. Systema Porifera currently includes five families in this …

Unusually cyclized triterpenoids: occurrence, biosynthesis and chemical synthesis

H Hussain, J Xiao, A Ali, IR Green… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2009 to 2021 Biosynthetically, most of the syntheses of triterpenes follow the
cascade cyclization and rearrangement of the acyclic precursors viz., squalene (S) and 2, 3 …