Concise review: a comprehensive analysis of reported adverse events in patients receiving unproven stem cell-based interventions
G Bauer, M Elsallab… - Stem cells translational …, 2018 - academic.oup.com
The promise of stem cell (SC) therapies to restore functions of damaged tissues and organs
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …
Cell-based therapeutic strategies for multiple sclerosis
NJ Scolding, M Pasquini, SC Reingold, JA Cohen - Brain, 2017 - academic.oup.com
The availability of multiple disease-modifying medications with regulatory approval to treat
multiple sclerosis illustrates the substantial progress made in therapy of the disease …
multiple sclerosis illustrates the substantial progress made in therapy of the disease …
[HTML][HTML] Clarifying stem-cell therapy's benefits and risks
PW Marks, CM Witten, RM Califf - New England Journal of …, 2017 - Mass Medical Soc
Clarifying Stem-Cell Therapy’s Benefits and Risks | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …
main content The New England Journal of Medicine homepage Advanced Search SEARCH …
Safety of autologous human schwann cell transplantation in subacute thoracic spinal cord injury
The rationale for implantation of autologous human Schwann cells (SCs) in persons with
subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are …
subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are …
[HTML][HTML] Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …
families, the search for new therapies has been a source of hope and frustration. Almost all …
Balancing safety and innovation for cell-based regenerative medicine
P Marks, S Gottlieb - New England Journal of Medicine, 2018 - Mass Medical Soc
Balancing Safety and Innovation for Cell-Based Regenerative Medicine | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
[HTML][HTML] Tumorigenicity assessment of cell therapy products: The need for global consensus and points to consider
Y Sato, H Bando, M Di Piazza, G Gowing, C Herberts… - Cytotherapy, 2019 - Elsevier
Pluripotent stem cells offer the potential for an unlimited source for cell therapy products.
However, there is concern regarding the tumorigenicity of these products in humans, mainly …
However, there is concern regarding the tumorigenicity of these products in humans, mainly …
[HTML][HTML] Ethical and regulatory issues of stem cell-derived 3-dimensional organoid and tissue therapy for personalised regenerative medicine
Background Regenerative medicine has the potential to treat genetic disorders and replace
damaged or missing tissue. The use of donor or animal tissue raises many well-known …
damaged or missing tissue. The use of donor or animal tissue raises many well-known …
A mechanistic roadmap for the clinical application of cardiac cell therapies
E Marbán - Nature biomedical engineering, 2018 - nature.com
The development of cells for regenerative therapy has encountered many pitfalls on its path
to clinical translation. In cardiology, clinical studies of heart-targeted cell therapies began …
to clinical translation. In cardiology, clinical studies of heart-targeted cell therapies began …
Results from phase I clinical trial with intraspinal injection of neural stem cells in amyotrophic lateral sclerosis: a long-term outcome
L Mazzini, M Gelati, DC Profico, G Sorarù… - Stem cells …, 2019 - academic.oup.com
The main objective of this phase I trial was to assess the feasibility and safety of
microtransplanting human neural stem cell (hNSC) lines into the spinal cord of patients with …
microtransplanting human neural stem cell (hNSC) lines into the spinal cord of patients with …