Mild cognitive impairment associated with Parkinson's disease (PD) is a risk factor for the
development of dementia. Despite the importance of early identification of mild cognitive …

Braak's hypothesis has been extremely influential over the last two decades. However,
neuropathological and clinical evidence suggest that the model does not conform to all …

Parkinson's disease has a long prodromal stage with various subclinical motor and non-
motor manifestations; however, their evolution in the years before Parkinson's disease is …

Objective This multilanguage study used simple speech recording and high‐end pattern
analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus …

People with Parkinson's disease (PD) and their care partners frequently report cognitive
decline as one of their greatest concerns. Mild cognitive impairment affects approximately 20 …

Pathological involvement of the noradrenergic locus coeruleus occurs early in Parkinson's
disease, and widespread noradrenaline reductions are found at post-mortem. Rapid eye …

Objective To investigate whether REM sleep behavior disorder (RBD) is associated with
worse motor and cognitive decline in Parkinson disease (PD) Methods Four-hundred twenty …

Parkinson's disease is a neurodegenerative disease whose progression and clinical
characteristics have a close bidirectional and multilevel relationship with the process of …

A relationship between sleep disorders and cognitive dysfunctions was reported in
Parkinson's Disease (PD), however, some studies did not confirm the link. A meta-analytic …

Rapid eye movement sleep behavior disorder (RBD) is a sleep behavior disorder
characterized by abnormal behaviors and loss of muscle atonia during rapid eye movement …