COVID-19, myocarditis and pericarditis

DL Fairweather, DJ Beetler, DN Di Florio… - Circulation …, 2023 - Am Heart Assoc
Viral infections are a leading cause of myocarditis and pericarditis worldwide, conditions that
frequently coexist. Myocarditis and pericarditis were some of the early comorbidities …

Autophagy-independent functions of the autophagy machinery

L Galluzzi, DR Green - Cell, 2019 - cell.com
Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism
that culminates with the lysosomal degradation of superfluous or potentially dangerous …

Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

[HTML][HTML] Autophagy during viral infection—a double-edged sword

Y Choi, JW Bowman, JU Jung - Nature Reviews Microbiology, 2018 - nature.com
Autophagy is a powerful tool that host cells use to defend against viral infection. Double-
membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome …

The role of autophagy in viral infections

T Chen, S Tu, L Ding, M Jin, H Chen, H Zhou - Journal of biomedical …, 2023 - Springer
Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …

The life cycle of non-polio enteroviruses and how to target it

J Baggen, HJ Thibaut, JRPM Strating… - Nature Reviews …, 2018 - nature.com
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …

Exosomes and other extracellular vesicles in host–pathogen interactions

JS Schorey, Y Cheng, PP Singh, VL Smith - EMBO reports, 2015 - embopress.org
An effective immune response requires the engagement of host receptors by pathogen‐
derived molecules and the stimulation of an appropriate cellular response. Therefore, a …

Autophagy and autophagy-related proteins in the immune system

ST Shibutani, T Saitoh, H Nowag, C Münz… - Nature …, 2015 - nature.com
Autophagy is an intracellular bulk degradation system that is highly conserved in
eukaryotes. The discovery of autophagy-related ('ATG') proteins in the 1990s greatly …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Vesicle-cloaked virus clusters are optimal units for inter-organismal viral transmission

M Santiana, S Ghosh, BA Ho, V Rajasekaran, WL Du… - Cell host & …, 2018 - cell.com
In enteric viral infections, such as those with rotavirus and norovirus, individual viral particles
shed in stool are considered the optimal units of fecal-oral transmission. We reveal that …