A guide to therapeutic drug monitoring of β‐lactam antibiotics

AJ Fratoni, DP Nicolau, JL Kuti - Pharmacotherapy: The Journal …, 2021 - Wiley Online Library
Therapeutic drug monitoring (TDM) opens the door to personalized medicine, yet it is
infrequently applied to β‐lactam antibiotics, one of the most commonly prescribed drug …

Current state of analgesia and sedation in the pediatric intensive care unit

C Egbuta, KP Mason - Journal of Clinical Medicine, 2021 - mdpi.com
Critically ill pediatric patients often require complex medical procedures as well as invasive
testing and monitoring which tend to be painful and anxiety-provoking, necessitating the …

An update on population pharmacokinetic analyses of vancomycin, part I: in adults

A Aljutayli, A Marsot, F Nekka - Clinical pharmacokinetics, 2020 - Springer
Despite the wide clinical use of vancomycin, controversy remains regarding its optimal
dosage regimens. This can be attributed to the large between-and within-subject variability …

Pediatric extracorporeal membrane oxygenation

CL Jenks, L Raman, HJ Dalton - Critical Care Clinics, 2017 - criticalcare.theclinics.com
Extracorporeal life support (ECLS), commonly referred to as extracorporeal membrane
oxygenation (ECMO), is a modified form of cardiopulmonary bypass. Venous blood is …

Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy and extracorporeal membrane oxygenation

JA Jamal, CJP Economou, J Lipman… - Current opinion in …, 2012 - journals.lww.com
Improving antibiotic dosing in special situations in the ICU... : Current Opinion in Critical Care
Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy …

Pharmacokinetic changes of antibiotic, antiviral, antituberculosis and antifungal agents during extracorporeal membrane oxygenation in critically ill adult patients

J Hahn, JH Choi, MJ Chang - Journal of Clinical Pharmacy and …, 2017 - Wiley Online Library
What is known and objective Extracorporeal membrane oxygenation (ECMO) is a life‐saving
system used for critically ill patients with cardiac and/or respiratory failure. The …

Effects of ex vivo Extracorporeal Membrane Oxygenation Circuits on Sequestration of Antimicrobial Agents

Y Zhang, H Hu, Q Zhang, Q Ou, H Zhou, T Sha… - Frontiers in …, 2021 - frontiersin.org
Objectives: Our ex vivo study was designed to determine the sequestration of teicoplanin,
tigecycline, micafungin, meropenem, polymyxin B, caspofungin, cefoperazone sulbactam …

Are pressure injuries related to skin failure in critically ill patients?

JL Nowicki, D Mullany, A Spooner, TA Nowicki… - Australian Critical …, 2018 - Elsevier
Background Pressure injuries contribute significantly to patient morbidity and healthcare
costs. Critically ill patients are a high risk group for pressure injury development and may …

Pharmacokinetic/pharmacodynamic considerations of beta-lactam antibiotics in adult critically ill patients

AM Masich, MS Heavner, JP Gonzales… - … infectious disease reports, 2018 - Springer
Abstract Purpose of Review Beta-lactam antibiotics are commonly prescribed in critically ill
patients for a variety of infectious conditions. Our understanding of how critical illness alters …

Two cases of refractory cardiogenic shock secondary to bupropion successfully treated with veno-arterial extracorporeal membrane oxygenation

CW Heise, AB Skolnik, RA Raschke… - Journal of Medical …, 2016 - Springer
Bupropion inhibits the uptake of dopamine and norepinephrine. Clinical effects in overdose
include seizure, status epilepticus, tachycardia, arrhythmias, and cardiogenic shock. We …