The past quarter century has witnessed rapid developments of fluorescence microscopy
techniques that enable structural and functional imaging of biological specimens at …

Optical microscopy is widely used to visualize fine structures. When applied to bioimaging,
its performance is often degraded by sample-induced aberrations. In recent years, adaptive …

Adaptive optics is becoming a valuable tool for high resolution microscopy, providing
correction for aberrations introduced by the refractive index structure of specimens. This is …

This is a comprehensive review of the principles and applications of adaptive optics (AO) in
ophthalmology. It has been combined with flood illumination ophthalmoscopy, scanning …

Second-harmonic generation (SHG) microscopy began to emerge as a high-resolution
optical imaging modality in the late 1990s, about 10 years after two-photon excited …

The imaging depth of two-photon excitation fluorescence microscopy is partly limited by the
inhomogeneity of the refractive index in biological specimens. This inhomogeneity results in …

The combination of a good quality embryo and proper maternal health factors promise
higher chances of a successful in vitro fertilization (IVF) procedure leading to clinical …

Application of optical imaging in developmental biology marks an exciting frontier in
biomedical optics. Optical resolution and imaging depth allow for investigation of growing …

Adaptive optics (AO) methods are widely used in microscopes to improve image quality
through correction of phase aberrations. A range of wavefront-sensorless AO schemes exist …

Background Lipid droplets (LD) are organelles with an important role in normal metabolism
and disease. The lipid content of embryos has a major impact on viability and development …